SCOP 1.63: Superfamily c.116.1: alpha/beta knot

Lineage for Superfamily c.116.1: alpha/beta knot

1. Root: SCOP 1.63

2. Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

3. Fold c.116: alpha/beta knot [75216] (1 superfamily)
   core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot

4. Superfamily c.116.1: alpha/beta knot [75217] (3 families)
   known or predicted SAM-dependent methytransferases; all known members have dimeric structures

Families:

1. c.116.1.1: SpoU-like RNA 2'-O ribose methyltransferase [75218] (3 proteins)
   contains extra strand (3) in the parallel beta-sheet, order 321546

2. c.116.1.2: Hypothetical protein MTH1 (MT0001), dimerisation domain [75221] (1 protein)
   contains extra strand (3) in the parallel beta-sheet, order 321546; interrupted by an insert OB-fold domain

3. c.116.1.3: YbeA-like [82371] (1 protein)

More info for Superfamily c.116.1: alpha/beta knot

Timeline for Superfamily c.116.1: alpha/beta knot:

• Superfamily c.116.1: alpha/beta knot first appeared in SCOP 1.61
  
• Superfamily c.116.1: alpha/beta knot appears in SCOP 1.65
  
• Superfamily c.116.1: alpha/beta knot appears in the current release, SCOPe 2.08