SCOP 1.73: Protein: Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2)

Lineage for Protein: Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2)

Root: SCOP 1.73
Class b: All beta proteins [48724] (165 folds)
Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
barrel, closed; n=6, S=8; greek-key
duplication: consists of two domains of the same fold
Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)
Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (3 proteins)
Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (3 species)
contains an extra alpha-helical domain

Species:

Human coronavirus 229E [TaxId:11137] [89348] (1 PDB entry)
- Domains for 1p9s:
  1. Domain d1p9sa_: 1p9s A: [87999]
  2. Domain d1p9sb_: 1p9s B: [88000]
    complexed with dox, mse; mutant
SARS coronavirus [TaxId:227859] [89349] (6 PDB entries)
1. Domains for 1q2w:
  1. Domain d1q2wa_: 1q2w A: [88355]
  2. Domain d1q2wb_: 1q2w B: [88356]
    complexed with mpd
2. Domains for 1uj1:
  1. Domain d1uj1a_: 1uj1 A: [99450]
  2. Domain d1uj1b_: 1uj1 B: [99451]
3. Domains for 1uk2:
  1. Domain d1uk2a_: 1uk2 A: [99481]
  2. Domain d1uk2b_: 1uk2 B: [99482]
4. Domains for 1uk3:
  1. Domain d1uk3a_: 1uk3 A: [99483]
  2. Domain d1uk3b_: 1uk3 B: [99484]
5. Domains for 1uk4:
  1. Domain d1uk4a_: 1uk4 A: [99485]
  2. Domain d1uk4b_: 1uk4 B: [99486]
    complexed with ato
6. Domain for 2alv:
  - Domain d2alva1: 2alv A:2-301 [126982]
    automatically matched to d1q2wb_
    complexed with cy6
Transmissible gastroenteritis virus [TaxId:11149] [74980] (3 PDB entries)
1. Domains for 1lvo:
  1. Domain d1lvoa_: 1lvo A: [74284]
  2. Domain d1lvob_: 1lvo B: [74285]
  3. Domain d1lvoc_: 1lvo C: [74286]
  4. Domain d1lvod_: 1lvo D: [74287]
  5. Domain d1lvoe_: 1lvo E: [74288]
  6. Domain d1lvof_: 1lvo F: [74289]
    complexed with dox, mpd, so4
2. Domains for 1p9u:
  1. Domain d1p9ua_: 1p9u A: [88001]
  2. Domain d1p9ub_: 1p9u B: [88002]
  3. Domain d1p9uc_: 1p9u C: [88003]
  4. Domain d1p9ud_: 1p9u D: [88004]
  5. Domain d1p9ue_: 1p9u E: [88005]
  6. Domain d1p9uf_: 1p9u F: [88006]
    complexed with ch2, mpd, so4
3. Domains for 2amp:
  1. Domain d2ampa1: 2amp A:1-299 [127021]
    automatically matched to d1lvod_
    complexed with i12
  2. Domain d2ampb1: 2amp B:1-299 [127022]
    automatically matched to d1lvod_
    complexed with i12

More info for Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) from b.47.1.4: Viral cysteine protease of trypsin fold

Timeline for Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) from b.47.1.4: Viral cysteine protease of trypsin fold:

Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) from b.47.1.4: Viral cysteine protease of trypsin fold first appeared in SCOP 1.61, called Protein Coronavirus main proteinase from b.47.1.4: Viral cysteine protease of trypsin fold
Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) from b.47.1.4: Viral cysteine protease of trypsin fold appears in SCOP 1.71
Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) from b.47.1.4: Viral cysteine protease of trypsin fold appears in SCOP 1.75
Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) from b.47.1.4: Viral cysteine protease of trypsin fold appears in the current release, SCOPe 2.08