SCOP 1.75: Domain d1ld8a_: 1ld8 A:

Lineage for d1ld8a_ (1ld8 A:)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (24 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.6: Protein prenylyltransferase [48439] (1 family)

5. Family a.118.6.1: Protein prenylyltransferase [48440] (2 proteins)

6. Protein Protein farnesyltransferase alpha-subunit [48441] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69093] (20 PDB entries)
   Uniprot P49354

8. Domain d1ld8a_: 1ld8 A: [73838]
   Other proteins in same PDB: d1ld8b_
   complexed with acy, fpp, suc, u49, zn

Details for d1ld8a_

PDB Entry: 1ld8, 1.8 Å

PDB Description: co-crystal structure of human farnesyltransferase with farnesyldiphosphate and inhibitor compound 49

PDB Compounds: (A:) protein farnesyltransferase alpha subunit

SCOP Domain Sequences for d1ld8a_:

Sequence; same for both SEQRES and ATOM records:

>d1ld8a_ a.118.6.1 (A:) Protein farnesyltransferase alpha-subunit {Human (Homo sapiens) [TaxId: 9606]}
fvsldspsyvlyrdraewadidpvpqndgpnpvvqiiysdkfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllkslqkdlheemnyitaiieeqpknyqvwhhrrv
lvewlrdpsqelefiadilnqdaknyhawqhrqwviqefklwdnelqyvdqllkedvrnn
svwnqryfvisnttgyndravlerevqytlemiklvphnesawnylkgilqdrglskypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskh

Timeline for d1ld8a_:

• d1ld8a_ first appeared in SCOP 1.61
  
• d1ld8a_ appears in SCOP 1.73
  
• d1ld8a_ appears in SCOPe 2.01
  
• d1ld8a_ appears in the current release, SCOPe 2.08