SCOPe 2.03: Domain d1isna3: 1isn A:18-103

Lineage for d1isna3 (1isn A:18-103)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.15: beta-Grasp (ubiquitin-like) [54235] (14 superfamilies)
   core: beta(2)-alpha-beta(2); mixed beta-sheet 2143

4. Superfamily d.15.1: Ubiquitin-like [54236] (9 families)

5. Family d.15.1.4: First domain of FERM [54256] (6 proteins)

6. Protein Merlin [69660] (2 species)
   the neurofibromatosis 2 tumor suppressor protein

7. Species Mouse (Mus musculus) [TaxId:10090] [75361] (1 PDB entry)

8. Domain d1isna3: 1isn A:18-103 [71402]
   Other proteins in same PDB: d1isna1, d1isna2

Details for d1isna3

PDB Entry: 1isn, 2.9 Å

PDB Description: Crystal structure of merlin FERM domain

PDB Compounds: (A:) merlin

SCOPe Domain Sequences for d1isna3:

Sequence; same for both SEQRES and ATOM records:

>d1isna3 d.15.1.4 (A:18-103) Merlin {Mouse (Mus musculus) [TaxId: 10090]}
qpktftvrivtmdaemefncemkwkgkdlfdlvcrtlglretwffglqytikdtvawlkm
dkkvldhdvskeepvtfhflakfype

Timeline for d1isna3:

• d1isna3 first appeared in SCOP 1.61
  
• d1isna3 appears in SCOPe 2.02
  
• d1isna3 appears in SCOPe 2.04
  
• d1isna3 appears in the current release, SCOPe 2.08