SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family d.79.5.1: IpsF-like

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2180205Fold d.79: Bacillus chorismate mutase-like [55297] (9 superfamilies)
    core: beta-alpha-beta-alpha-beta(2); mixed beta-sheet: order: 1423, strand 4 is antiparallel to the rest
  4. 2180995Superfamily d.79.5: IpsF-like [69765] (2 families) (S)
    forms trimers with three closely packed beta-sheets; possible link between the YjgF-like (d.79.1) and 4'-phosphopantetheinyl transferase superfamilies (d.150.1)
  5. 2180996Family d.79.5.1: IpsF-like [69766] (3 protein domains)
    automatically mapped to Pfam PF02542

Protein Domains:

  1. 21809972C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF [69767] (6 species)
    1. 2180998Species Escherichia coli K-12 [TaxId:83333] [188969] (5 PDB entries)
    2. 2181011Species Escherichia coli [TaxId:562] [69768] (14 PDB entries)
      Uniprot P62617 ! Uniprot P36663
    3. 2181043Species Haemophilus influenzae [TaxId:727] [75479] (3 PDB entries)
    4. 2181059Species Shewanella oneidensis [TaxId:70863] [118026] (1 PDB entry)
      Uniprot Q8EBR3
    5. 2181063Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [187992] (1 PDB entry)
    6. 2181065Species Thermus thermophilus [TaxId:274] [82720] (4 PDB entries)
  2. 2181090IspD/ispF bifunctional enzyme, MECDP synthase domain [118027] (1 species)
  3. 2181094automated matches [190985] (4 species)
    not a true protein
    1. 2181095Species Burkholderia pseudomallei [TaxId:28450] [189021] (2 PDB entries)
    2. 2181102Species Salmonella typhimurium [TaxId:90371] [189751] (2 PDB entries)
    3. 2181112Species Yersinia pestis [TaxId:214092] [188680] (2 PDB entries)
    4. 2289034Species Bacillus subtilis [TaxId:224308] [332335] (2 PDB entries)

More info for Family d.79.5.1: IpsF-like

Timeline for Family d.79.5.1: IpsF-like: