SCOPe 2.04: Domain d1joea_: 1joe A:

Lineage for d1joea_ (1joe A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.185: LuxS/MPP-like metallohydrolase [63410] (1 superfamily)
   core: beta-alpha-beta(2)-alpha(2); 2 layers: alpha/beta

4. Superfamily d.185.1: LuxS/MPP-like metallohydrolase [63411] (3 families)
   Share the same "active site motif" HxxEH located in the first core helix, but differ in one of the zinc-binding residues

5. Family d.185.1.2: Autoinducer-2 production protein LuxS [64294] (1 protein)
   contains additional N-terminal strand; possible relationships to the putative editing domain of ThrRS (d.67.1)
   automatically mapped to Pfam PF02664

6. Protein Autoinducer-2 production protein LuxS [64295] (4 species)
   S-ribosylhomocysteinase

7. Species Haemophilus influenzae [TaxId:727] [64298] (2 PDB entries)

8. Domain d1joea_: 1joe A: [63210]
   complexed with hg, zn

Details for d1joea_

PDB Entry: 1joe, 2.4 Å

PDB Description: crystal structure of autoinducer-2 production protein (luxs) from heamophilus influenzae

PDB Compounds: (A:) autoinducer-2 production protein

SCOPe Domain Sequences for d1joea_:

Sequence; same for both SEQRES and ATOM records:

>d1joea_ d.185.1.2 (A:) Autoinducer-2 production protein LuxS {Haemophilus influenzae [TaxId: 727]}
vdhtkmnapavriaktmltpkgdnitvfdlrfcipnkeilspkgihtlehlfagfmrdhl
ngdsieiidispmgcrtgfymsligtpneqkvseawlasmqdvlgvqdqasipelniyqc
gsytehsledaheiaknviargigvnkn

Timeline for d1joea_:

• d1joea_ first appeared in SCOP 1.57
  
• d1joea_ appears in SCOPe 2.03
  
• d1joea_ appears in SCOPe 2.05
  
• d1joea_ appears in the current release, SCOPe 2.08