SCOP 1.71: Domain d1i85d_: 1i85 D:

Lineage for d1i85d_ (1i85 D:)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (28 proteins)

6. Protein Immunoreceptor CTLA-4 (CD152), N-terminal fragment [48939] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48940] (3 PDB entries)

8. Domain d1i85d_: 1i85 D: [61949]
   Other proteins in same PDB: d1i85a_, d1i85b_
   b7-2 complex

Details for d1i85d_

PDB Entry: 1i85, 3.2 Å

PDB Description: crystal structure of the ctla-4/b7-2 complex

SCOP Domain Sequences for d1i85d_:

Sequence, based on SEQRES records:

>d1i85d_ b.1.1.1 (D:) Immunoreceptor CTLA-4 (CD152), N-terminal fragment {Human (Homo sapiens)}
mhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgneltf
lddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpe

Sequence, based on observed residues (ATOM records):

>d1i85d_ b.1.1.1 (D:) Immunoreceptor CTLA-4 (CD152), N-terminal fragment {Human (Homo sapiens)}
mhvaqpavvlassrgiasfvceyaatevrvtvlrqqvtevcaatymmgneltflddsict
gtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpe

Timeline for d1i85d_:

• d1i85d_ first appeared in SCOP 1.57
  
• d1i85d_ appears in SCOP 1.69
  
• d1i85d_ appears in SCOP 1.73
  
• d1i85d_ appears in the current release, SCOPe 2.08