Lineage for Fold g.3: Knottins (small inhibitors, toxins, lectins)

  1. Root: SCOP 1.75
  2. 888632Class g: Small proteins [56992] (90 folds)
  3. 888904Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
    disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

Superfamilies:

  1. 888905g.3.1: Plant lectins/antimicrobial peptides [57016] (2 families) (S)
  2. 889030g.3.2: Plant inhibitors of proteinases and amylases [57027] (1 family) (S)
  3. 889080g.3.3: Cyclotides [57038] (4 families) (S)
    macrocyclic plant knottins closed with the formation of an Asn-Gly peptide
  4. 889108g.3.4: Gurmarin-like [57048] (2 families) (S)
  5. 889121g.3.5: Agouti-related protein [57055] (1 family) (S)
  6. 889127g.3.6: omega toxin-like [57059] (5 families) (S)
  7. 889275g.3.7: Scorpion toxin-like [57095] (5 families) (S)
  8. 889528g.3.8: Cellulose-binding domain [57180] (1 family) (S)
  9. 889538g.3.9: Growth factor receptor domain [57184] (1 family) (S)
  10. 889600g.3.10: Colipase-like [57190] (1 family) (S)
  11. 889622g.3.11: EGF/Laminin [57196] (7 families) (S)
  12. 890069g.3.12: Bromelain inhibitor VI (cysteine protease inhibitor) [57243] (1 family) (S)
  13. 890077g.3.13: Bowman-Birk inhibitor, BBI [57247] (1 family) (S)
  14. 890111g.3.14: Elafin-like [57256] (1 family) (S)
  15. 890120g.3.15: Leech antihemostatic proteins [57262] (2 families) (S)
  16. 890161g.3.16: Granulin repeat [57277] (1 family) (S)
  17. 890173g.3.17: Satiety factor CART (cocaine and amphetamine regulated transcript) [64546] (1 family) (S)
  18. 890178g.3.18: DPY module [90148] (1 family) (S)
  19. 890183g.3.19: Bubble protein [103565] (1 family) (S)

More info for Fold g.3: Knottins (small inhibitors, toxins, lectins)

Timeline for Fold g.3: Knottins (small inhibitors, toxins, lectins):