Lineage for Fold g.3: Knottins (small inhibitors, toxins, lectins)

  1. Root: SCOPe 2.01
  2. 1061255Class g: Small proteins [56992] (90 folds)
  3. 1061532Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
    disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

Superfamilies:

  1. 1061533g.3.1: Plant lectins/antimicrobial peptides [57016] (2 families) (S)
  2. 1061661g.3.2: Plant inhibitors of proteinases and amylases [57027] (1 family) (S)
  3. 1061713g.3.3: Cyclotides [57038] (4 families) (S)
    macrocyclic plant knottins closed with the formation of an Asn-Gly peptide
  4. 1061744g.3.4: Gurmarin-like [57048] (2 families) (S)
  5. 1061757g.3.5: Agouti-related protein [57055] (1 family) (S)
  6. 1061763g.3.6: omega toxin-like [57059] (5 families) (S)
  7. 1061911g.3.7: Scorpion toxin-like [57095] (5 families) (S)
  8. 1062187g.3.8: Cellulose-binding domain [57180] (1 family) (S)
  9. 1062197g.3.9: Growth factor receptor domain [57184] (1 family) (S)
  10. 1062261g.3.10: Colipase-like [57190] (1 family) (S)
  11. 1062283g.3.11: EGF/Laminin [57196] (7 families) (S)
  12. 1062778g.3.12: Bromelain inhibitor VI (cysteine protease inhibitor) [57243] (1 family) (S)
  13. 1062786g.3.13: Bowman-Birk inhibitor, BBI [57247] (1 family) (S)
  14. 1062816g.3.14: Elafin-like [57256] (1 family) (S)
  15. 1062825g.3.15: Leech antihemostatic proteins [57262] (3 families) (S)
  16. 1062873g.3.16: Granulin repeat [57277] (1 family) (S)
  17. 1062885g.3.17: Satiety factor CART (cocaine and amphetamine regulated transcript) [64546] (1 family) (S)
  18. 1062890g.3.18: DPY module [90148] (1 family) (S)
  19. 1062895g.3.19: Bubble protein [103565] (1 family) (S)

More info for Fold g.3: Knottins (small inhibitors, toxins, lectins)

Timeline for Fold g.3: Knottins (small inhibitors, toxins, lectins):