SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Fold g.2: Toxic hairpin

  1. Root: SCOPe 2.06
  2. 2229111Class g: Small proteins [56992] (94 folds)
  3. 2229368Fold g.2: Toxic hairpin [57006] (4 superfamilies)
    disulfide crosslinked alpha-helical hairpin


  1. 2229369g.2.1: Heat-stable enterotoxin B [57007] (1 family) (S)
    automatically mapped to Pfam PF09075
  2. 2229374g.2.2: Neurotoxin B-IV [57011] (1 family) (S)
  3. 2229379g.2.3: Pollen allergen ole e 6 [111388] (1 family) (S)
    contains 3 disulfides
    automatically mapped to Pfam PF09253
  4. 2229384g.2.4: VhTI-like [161148] (1 family) (S)

More info for Fold g.2: Toxic hairpin

Timeline for Fold g.2: Toxic hairpin: