Lineage for Fold f.4: Transmembrane beta-barrels

  1. Root: SCOPe 2.06
  2. 2223823Class f: Membrane and cell surface proteins and peptides [56835] (59 folds)
  3. 2224301Fold f.4: Transmembrane beta-barrels [56924] (7 superfamilies)
    not a true fold, gathers together transmembrane barrels of different (n,S)

Superfamilies:

  1. 2224302f.4.1: OMPA-like [56925] (5 families) (S)
    forms (8,10) barrel
  2. 2224393f.4.2: Outer membrane phospholipase A (OMPLA) [56931] (1 family) (S)
    forms (12,16) barrel
  3. 2224406f.4.3: Porins [56935] (5 families) (S)
  4. 2224627f.4.4: OMPT-like [69917] (3 families) (S)
    forms (10,12) barrel
  5. 2224647f.4.5: Autotransporter [103515] (1 family) (S)
    forms (12,14) barrel; contains a long alpha-helix running along the barrel axis
    automatically mapped to Pfam PF03797
  6. 2224653f.4.6: Tsx-like channel [111364] (1 family) (S)
    forms (12,16) barrel
    automatically mapped to Pfam PF03502
  7. 2224663f.4.7: Outer membrane carboxylate (Occ) channels [310584] (3 families) (S)
    Pfam PF03573; Phylogeny discussed in PubMed 22272184
    labile trimers according to PubMed 17952093; each subunit forms (18,22) barrel

More info for Fold f.4: Transmembrane beta-barrels

Timeline for Fold f.4: Transmembrane beta-barrels: