Lineage for Family e.8.1.2: Reverse transcriptase

  1. Root: SCOPe 2.07
  2. 2568173Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)
  3. 2571153Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 2571154Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 2571504Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

Proteins:

  1. 2571505HIV-1 reverse transcriptase [56689] (4 species)
    1. 2571506Species Hiv-1 m:b_hxb2r [TaxId:11706] [190022] (22 PDB entries)
    2. 2571547Species Human immunodeficiency virus type 1 group m subtype b (isolate lw123) [TaxId:82834] [319106] (1 PDB entry)
    3. 2571549Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (189 PDB entries)
      Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595
    4. 2571890Species Human immunodeficiency virus type 2 [TaxId:11709] [82840] (1 PDB entry)
  2. 2571893MMLV reverse transcriptase [56687] (1 species)
  3. 2571920automated matches [190211] (6 species)
    not a true protein
    1. 2571921Species Hiv-1 m:b_hxb2r [TaxId:11706] [187165] (10 PDB entries)
    2. 2571940Species Human immunodeficiency virus 1 [TaxId:11676] [186967] (7 PDB entries)
    3. 2571951Species Human immunodeficiency virus type 1 bh10 [TaxId:11678] [225820] (18 PDB entries)
    4. 2571976Species Human immunodeficiency virus type 1 group m subtype b (isolate bh10) [TaxId:11678] [311492] (3 PDB entries)
    5. 2571981Species Human immunodeficiency virus type 1 [TaxId:11678] [226272] (13 PDB entries)
    6. 2572005Species Moloney murine leukemia virus [TaxId:11801] [188900] (1 PDB entry)

More info for Family e.8.1.2: Reverse transcriptase

Timeline for Family e.8.1.2: Reverse transcriptase: