Lineage for Protein: Neutral endopeptidase (neprilysin)
- Root: SCOPe 2.04
Class d: Alpha and beta proteins (a+b) [53931] (380 folds) 
Fold d.92: Zincin-like [55485] (2 superfamilies)
contains mixed beta sheet with connection over free side of the sheetSuperfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families) 
Family d.92.1.4: Neutral endopeptidase (neprilysin) [55502] (2 proteins) Protein Neutral endopeptidase (neprilysin) [55503] (1 species)
contains thermolysin-like catalytic domain (residues 419-749)
the N-terminal half of the structure is multihelical
Species:
Human (Homo sapiens) [TaxId:9606] [55504] (6 PDB entries)
Uniprot P08473 54-749- Domain for 1dmt:
Domain d1dmta_: 1dmt A: [40296]
complexed with gol, nag, rdf, zn
- Domain for 1r1h:
Domain d1r1ha_: 1r1h A: [104756]
complexed with bir, nag, zn
- Domain for 1r1i:
Domain d1r1ia_: 1r1i A: [104757]
complexed with nag, ti1, zn
- Domain for 1r1j:
Domain d1r1ja_: 1r1j A: [104758]
complexed with nag, oir, zn
- Domain for 1y8j:
Domain d1y8ja_: 1y8j A: [122752]
automated match to d1dmta_
complexed with act, nag, sts, zn
- Domain for 2qpj:
Domain d2qpja_: 2qpj A: [151205]
automated match to d1dmta_
complexed with i20, nag, zn
- Domain for 1dmt:
More info for Protein Neutral endopeptidase (neprilysin) from d.92.1.4: Neutral endopeptidase (neprilysin)
Timeline for Protein Neutral endopeptidase (neprilysin) from d.92.1.4: Neutral endopeptidase (neprilysin):
- Protein Neutral endopeptidase (neprilysin) from d.92.1.4: Neutral endopeptidase (neprilysin) first appeared (with stable ids) in SCOP 1.55
- Protein Neutral endopeptidase (neprilysin) from d.92.1.4: Neutral endopeptidase (neprilysin) appears in SCOPe 2.03
- Protein Neutral endopeptidase (neprilysin) from d.92.1.4: Neutral endopeptidase (neprilysin) appears in SCOPe 2.05
- Protein Neutral endopeptidase (neprilysin) from d.92.1.4: Neutral endopeptidase (neprilysin) appears in the current release, SCOPe 2.08