Class d: Alpha and beta proteins (a+b) [53931] (396 folds) |
Fold d.26: FKBP-like [54533] (3 superfamilies) core: beta(2)-alpha-beta(2); antiparallel beta-sheet |
Superfamily d.26.1: FKBP-like [54534] (4 families) |
Family d.26.1.1: FKBP immunophilin/proline isomerase [54535] (17 proteins) |
Archaeal FKBP [89879] (1 species) contains insert all-beta subdomain; dual function: PPI and chaperone-like activities |
Species Methanococcus thermolithotrophicus [TaxId:2186] [89880] (1 PDB entry) |
Calcineurin (FKBP12.6) [54539] (3 species) |
Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [54542] (1 PDB entry) |
Species Cow (Bos taurus) [TaxId:9913] [54541] (1 PDB entry) |
Species Human (Homo sapiens) [TaxId:9606] [54540] (4 PDB entries) |
FK-506 binding protein (FKBP12), an immunophilin [54536] (2 species) cis-trans prolyl-isomerase |
Species Cow (Bos taurus) [TaxId:9913] [54538] (2 PDB entries) |
Species Human (Homo sapiens) [TaxId:9606] [54537] (42 PDB entries) |
FKB-6, N-terminal domain [102864] (1 species) |
Species Nematode (Caenorhabditis elegans) [TaxId:6239] [102865] (1 PDB entry) |
FKBP13 [110870] (1 species) |
Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [110871] (2 PDB entries) Uniprot Q9SCY2 84-208 |
FKBP25 [54543] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [54544] (3 PDB entries) |
FKBP51, N-terminal domains [82621] (2 species) duplication: tandem repeat of two FKBP domains |
Species Human (Homo sapiens) [TaxId:9606] [82622] (1 PDB entry) |
Species Monkey (Saimiri boliviensis) [TaxId:27679] [82623] (1 PDB entry) |
FKBP52, N-terminal domains [82619] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [82620] (11 PDB entries) Uniprot Q02790 21-427; contains tandem repeat of two FKPB domains |
FKBP59-I, N-terminal domain [54545] (1 species) |
Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [54546] (2 PDB entries) |
Macrophage infectivity potentiator protein (MIP) [64250] (2 species) contains all-alpha dimerisation subdomain in the N-terminal extension |
Species Legionella pneumophila [TaxId:446] [64251] (1 PDB entry) |
Species Trypanosoma cruzi [TaxId:5693] [75387] (1 PDB entry) |
Mitotic rotamase PIN1, domain 2 [54547] (2 species) Domain 1 is a WW-domain |
Species Human (Homo sapiens) [TaxId:9606] [54548] (52 PDB entries) |
Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [75386] (1 PDB entry) |
Parvulin [64248] (1 species) |
Species Human (Homo sapiens), hpar14 [TaxId:9606] [64249] (2 PDB entries) |
Parvulin 10 (rotamase C) [89877] (1 species) |
Species Escherichia coli [TaxId:562] [89878] (2 PDB entries) |
Peptidyl-prolyl cis-trans isomerase FkpA [102866] (1 species) similar to MIP; contains all-alpha dimerisation subdomain in the N-terminal extension |
Species Escherichia coli [TaxId:562] [102867] (3 PDB entries) |
Porin chaperone SurA, PPIase domains [82624] (1 species) |
Species Escherichia coli [TaxId:562] [82625] (4 PDB entries) |
Trigger factor PPIase domain [75388] (3 species) |
Species Escherichia coli [TaxId:562] [89881] (3 PDB entries) Uniprot P22257 |
Species Mycoplasma genitalium [TaxId:2097] [75389] (1 PDB entry) |
Species Vibrio cholerae [TaxId:666] [110869] (1 PDB entry) Uniprot Q9KQS5 |
automated matches [191209] (6 species) not a true protein |
Species Candida auris [TaxId:498019] [383232] (1 PDB entry) |
Species Candida glabrata [TaxId:284593] [322580] (2 PDB entries) |
Species Human (Homo sapiens) [TaxId:9606] [189839] (61 PDB entries) |
Species Mouse (Mus musculus) [TaxId:10090] [189566] (1 PDB entry) |
Species Mucor circinelloides [TaxId:36080] [397778] (2 PDB entries) |
Species Yellow fever mosquito (Aedes aegypti) [TaxId:7159] [195032] (2 PDB entries) |
Timeline for Family d.26.1.1: FKBP immunophilin/proline isomerase: