Lineage for Fold d.15: beta-Grasp (ubiquitin-like)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.15: beta-Grasp (ubiquitin-like) [54235] (15 superfamilies)
    core: beta(2)-alpha-beta(2); mixed beta-sheet 2143

Superfamilies:

  1. d.15.1: Ubiquitin-like [54236] (11 families) (S)
  2. d.15.2: CAD & PB1 domains [54277] (3 families) (S)
    contain extra helix; similar heterodimerization modes; possibly related to the ubiquitin-like superfamily
  3. d.15.3: MoaD/ThiS [54285] (5 families) (S)
    possible link between the ubiquitin-like and 2Fe-2S ferredoxin-like superfamilies
  4. d.15.4: 2Fe-2S ferredoxin-like [54292] (3 families) (S)
  5. d.15.5: Staphylokinase/streptokinase [54328] (1 family) (S)
    automatically mapped to Pfam PF02821
  6. d.15.6: Superantigen toxins, C-terminal domain [54334] (2 families) (S)
  7. d.15.7: Immunoglobulin-binding domains [54358] (1 family) (S)
  8. d.15.8: Translation initiation factor IF3, N-terminal domain [54364] (2 families) (S)
    automatically mapped to Pfam PF05198
  9. d.15.9: Glutamine synthetase, N-terminal domain [54368] (2 families) (S)
    automatically mapped to Pfam PF03951
  10. d.15.10: TGS-like [81271] (3 families) (S)
    possibly related to the ubiquitin-like and MoaD/ThiS superfamilies; some similarity to the alpha-L RNA-binding motif
  11. d.15.11: Doublecortin (DC) [89837] (1 family) (S)
    possibly related to the ubiquitin-like superfamily
  12. d.15.12: TmoB-like [110814] (2 families) (S)
    possibly related to the ubiquitin-like and/or 2Fe-2S ferredoxin-like superfamilies
  13. d.15.13: Nqo1 middle domain-like [142984] (2 families) (S)
    possibly evolved from 2Fe-2S ferredoxins; contains no iron-sulfur cluster
  14. d.15.14: NSP3A-like [159936] (1 family) (S)
    short helical inserions in the common fold
  15. d.15.15: Phosphoinositide 3-kinase alpha adaptor-binding domain (ABD)-like [418745] (1 family) (S)

More info for Fold d.15: beta-Grasp (ubiquitin-like)

Timeline for Fold d.15: beta-Grasp (ubiquitin-like):