Lineage for Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenases
- Root: SCOP 1.65
Class c: Alpha and beta proteins (a/b) [51349] (121 folds) 
Fold c.77: Isocitrate/Isopropylmalate dehydrogenases [53658] (1 superfamily)
consists of two intertwined (sub)domains related by pseudo dyad; duplication
3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the restSuperfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenases [53659] (2 families) 
Families:
c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (3 proteins)
the active site is between the two identical subunits
c.77.1.2: Monomeric isocitrate dehydrogenase [82526] (1 protein)
the active site is contained within one subunit between the canonical ICDH fold and a large insert domain that itself is a probable rudiment form of ICDH fold resulted from duplication, domain swapping and deletion
More info for Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenases
Timeline for Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenases:
- Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenases first appeared (with stable ids) in SCOP 1.55, called Superfamily c.77.1: Isocitrate & isopropylmalate dehydrogenases
- Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenases appears in SCOP 1.63
- Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenases is called Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like in SCOP 1.67
- Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenases appears in the current release, SCOPe 2.08, called Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like