Lineage for Superfamily c.55.3: Ribonuclease H-like

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2460924Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest
  4. 2462855Superfamily c.55.3: Ribonuclease H-like [53098] (16 families) (S)
    consists of one domain of this fold

Families:

  1. 2462856c.55.3.1: Ribonuclease H [53099] (5 protein domains)
  2. 2463135c.55.3.2: Retroviral integrase, catalytic domain [53107] (2 protein domains)
  3. 2463445c.55.3.3: mu transposase, core domain [53112] (1 protein)
    automatically mapped to Pfam PF02914
  4. 2463451c.55.3.4: Transposase inhibitor (Tn5 transposase) [53115] (1 protein)
  5. 2463460c.55.3.5: DnaQ-like 3'-5' exonuclease [53118] (17 protein domains)
    contains Pfam PF00929
  6. 2463886c.55.3.6: RuvC resolvase [53134] (1 protein)
    automatically mapped to Pfam PF02075
  7. 2463899c.55.3.7: Mitochondrial resolvase ydc2 catalytic domain [69533] (1 protein)
    automatically mapped to Pfam PF09159
  8. 2463904c.55.3.8: Putative Holliday junction resolvase RuvX [102485] (3 protein domains)
    automatically mapped to Pfam PF03652
  9. 2463919c.55.3.9: CAF1-like ribonuclease [102492] (3 protein domains)
  10. 2463930c.55.3.11: TM1739-like [142505] (1 protein)
    Pfam PF04251; DUF430; particular similarity to the PIWI domain family
  11. 2463935c.55.3.12: Hermes transposase-like [142508] (1 protein)
  12. 2463939c.55.3.13: Tex RuvX-like domain-like [159635] (1 protein)
  13. 2463945c.55.3.14: Prp8 beta-finger domain-like [159638] (1 protein)
    automatically mapped to Pfam PF12134
  14. 2463988c.55.3.15: PIWI domain C-terminal [310608] (4 protein domains)
    PubMed 15565169 notes that both halves of PIWI are usually a single evolutionary unit; however, fragments have been characterized separately. The N-terminal half is (c.44.3.1)
  15. 2464015c.55.3.16: RuvC-like domain from CRISPR-associated protein Cas9 [345969] (1 protein)
    Homology to RuvC noted in PubMed 21756346
  16. 2464026c.55.3.0: automated matches [191357] (1 protein)
    not a true family

More info for Superfamily c.55.3: Ribonuclease H-like

Timeline for Superfamily c.55.3: Ribonuclease H-like: