SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Fold c.52: Restriction endonuclease-like

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2121131Fold c.52: Restriction endonuclease-like [52979] (4 superfamilies)
    core: 3 layers, a/b/a; mixed beta-sheet of 5 strands, order 12345; strands 2 &, in some families, 5 are antiparallel to the rest

Superfamilies:

  1. 2121132c.52.1: Restriction endonuclease-like [52980] (36 families) (S)
  2. 2121679c.52.2: tRNA-intron endonuclease catalytic domain-like [53032] (1 family) (S)
  3. 2121717c.52.3: Eukaryotic RPB5 N-terminal domain [53036] (1 family) (S)
  4. 2121760c.52.4: TBP-interacting protein-like [159612] (1 family) (S)
    contains extra C-terminal alpha+beta domain of complex fold with an embeded C2H2 zinc-finger

More info for Fold c.52: Restriction endonuclease-like

Timeline for Fold c.52: Restriction endonuclease-like: