Lineage for Fold c.36: Thiamin diphosphate-binding fold (THDP-binding)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465

Superfamily:

  • 2108259c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules

More info for Fold c.36: Thiamin diphosphate-binding fold (THDP-binding)

Timeline for Fold c.36: Thiamin diphosphate-binding fold (THDP-binding):