Lineage for Protein: Dihydrodipicolinate synthase

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2826025Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2834402Superfamily c.1.10: Aldolase [51569] (9 families) (S)
    Common fold covers whole protein structure
  5. 2834403Family c.1.10.1: Class I aldolase [51570] (13 proteins)
    the catalytic lysine forms schiff-base intermediate with substrate
    possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels
  6. 2834536Protein Dihydrodipicolinate synthase [51574] (13 species)

Species:

  1. 2834537Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [141832] (2 PDB entries)
    Uniprot Q81WN7 1-292
    1. Domains for 1xky:
      1. 2834538Domain d1xkya1: 1xky A:1-292 [122094]
        complexed with k
        has additional insertions and/or extensions that are not grouped together
      2. 2834539Domain d1xkyb_: 1xky B: [122095]
        automated match to d1xkya1
        complexed with k

        has additional insertions and/or extensions that are not grouped together
      3. 2834540Domain d1xkyc_: 1xky C: [122096]
        automated match to d1xkya1
        complexed with k

        has additional insertions and/or extensions that are not grouped together
      4. 2834541Domain d1xkyd_: 1xky D: [122097]
        automated match to d1xkya1
        complexed with k

        has additional insertions and/or extensions that are not grouped together
    2. Domains for 1xl9:
      1. 2834542Domain d1xl9a_: 1xl9 A: [122108]
        automated match to d1xkya1
        has additional insertions and/or extensions that are not grouped together
      2. 2834543Domain d1xl9b_: 1xl9 B: [122109]
        automated match to d1xkya1
        has additional insertions and/or extensions that are not grouped together
      3. 2834544Domain d1xl9c_: 1xl9 C: [122110]
        automated match to d1xkya1
        has additional insertions and/or extensions that are not grouped together
      4. 2834545Domain d1xl9d_: 1xl9 D: [122111]
        automated match to d1xkya1
        has additional insertions and/or extensions that are not grouped together
  2. 2834546Campylobacter jejuni [TaxId:192222] [189204] (3 PDB entries)
    1. Domains for 3ler:
      1. 2834547Domain d3lera_: 3ler A: [180235]
        automated match to d1o5ka_
        complexed with acy, edo, fmt, mg, peg

        has additional insertions and/or extensions that are not grouped together
      2. 2834548Domain d3lerb_: 3ler B: [180236]
        automated match to d1o5ka_
        complexed with acy, edo, fmt, mg, peg

        has additional insertions and/or extensions that are not grouped together
      3. 2834549Domain d3lerc_: 3ler C: [180237]
        automated match to d1o5ka_
        complexed with acy, edo, fmt, mg, peg

        has additional insertions and/or extensions that are not grouped together
      4. 2834550Domain d3lerd_: 3ler D: [180238]
        automated match to d1o5ka_
        complexed with acy, edo, fmt, mg, peg

        has additional insertions and/or extensions that are not grouped together
    2. Domains for 5f1u:
      1. 2834555Domain d5f1ua_: 5f1u A: [313912]
        automated match to d3lera_
        complexed with 3vn, cl, edo, pg4, pge

        has additional insertions and/or extensions that are not grouped together
      2. 2834556Domain d5f1ub_: 5f1u B: [313876]
        automated match to d3lera_
        complexed with 3vn, cl, edo, pg4, pge

        has additional insertions and/or extensions that are not grouped together
      3. 2834557Domain d5f1uc_: 5f1u C: [313891]
        automated match to d3lera_
        complexed with 3vn, cl, edo, pg4, pge

        has additional insertions and/or extensions that are not grouped together
      4. 2834558Domain d5f1ud_: 5f1u D: [313935]
        automated match to d3lera_
        complexed with 3vn, cl, edo, pg4, pge

        has additional insertions and/or extensions that are not grouped together
    3. Domains for 5f1v:
      1. 2834551Domain d5f1va_: 5f1v A: [313873]
        automated match to d3lera_
        complexed with 3vn, edo, gol, pge

        has additional insertions and/or extensions that are not grouped together
      2. 2834552Domain d5f1vb_: 5f1v B: [313996]
        automated match to d3lera_
        complexed with 3vn, edo, gol, pge

        has additional insertions and/or extensions that are not grouped together
      3. 2834553Domain d5f1vc_: 5f1v C: [314125]
        automated match to d3lera_
        complexed with 3vn, edo, gol, pge

        has additional insertions and/or extensions that are not grouped together
      4. 2834554Domain d5f1vd_: 5f1v D: [314016]
        automated match to d3lera_
        complexed with 3vn, edo, gol, pge

        has additional insertions and/or extensions that are not grouped together
  3. 2834559Clostridium botulinum [TaxId:441770] [189380] (1 PDB entry)
    • Domains for 3a5f:
      1. 2834560Domain d3a5fa_: 3a5f A: [171751]
        automated match to d1o5ka_
        complexed with gol

        has additional insertions and/or extensions that are not grouped together
      2. 2834561Domain d3a5fb_: 3a5f B: [171752]
        automated match to d1o5ka_
        complexed with gol

        has additional insertions and/or extensions that are not grouped together
  4. 2834562Clostridium botulinum [TaxId:441771] [189048] (2 PDB entries)
    1. Domain for 3bi8:
      • 2834563Domain d3bi8a_: 3bi8 A: [305092]
        automated match to d3irda_
        complexed with gol, mlt, na

        has additional insertions and/or extensions that are not grouped together
    2. Domain for 3ird:
      • 2834564Domain d3irda_: 3ird A: [178582]
        automated match to d1o5ka_
        complexed with cl, gol, mlt, na

        has additional insertions and/or extensions that are not grouped together
  5. 2834565Corynebacterium glutamicum [TaxId:1718] [188663] (1 PDB entry)
  6. 2834568Escherichia coli K-12 [TaxId:83333] [188673] (3 PDB entries)
    1. Domains for 3den:
      1. 2834571Domain d3dena_: 3den A: [173872]
        automated match to d1dhpa_
        complexed with gol, k, po4; mutant

        has additional insertions and/or extensions that are not grouped together
      2. 2834572Domain d3denb_: 3den B: [173873]
        automated match to d1dhpa_
        complexed with gol, k, po4; mutant

        has additional insertions and/or extensions that are not grouped together
    2. Domains for 3i7r:
      1. 2834569Domain d3i7ra_: 3i7r A: [178135]
        automated match to d1dhpa_
        complexed with cl, gol, k, po4

        has additional insertions and/or extensions that are not grouped together
      2. 2834570Domain d3i7rb_: 3i7r B: [178136]
        automated match to d1dhpa_
        complexed with cl, gol, k, po4

        has additional insertions and/or extensions that are not grouped together
    3. Domains for 3i7s:
      1. 2834573Domain d3i7sa_: 3i7s A: [178137]
        automated match to d1dhpa_
        complexed with gol, k, po4, pyr; mutant

        has additional insertions and/or extensions that are not grouped together
      2. 2834574Domain d3i7sb_: 3i7s B: [178138]
        automated match to d1dhpa_
        complexed with gol, k, po4, pyr; mutant

        has additional insertions and/or extensions that are not grouped together
  7. 2834575Escherichia coli [TaxId:562] [51575] (17 PDB entries)
    1. Domains for 1dhp:
      1. 2834592Domain d1dhpa_: 1dhp A: [29097]
        complexed with k
        has additional insertions and/or extensions that are not grouped together
      2. 2834593Domain d1dhpb_: 1dhp B: [29098]
        complexed with k
        has additional insertions and/or extensions that are not grouped together
    2. Domains for 1s5t:
      1. 2834586Domain d1s5ta_: 1s5t A: [98571]
        mutant
        has additional insertions and/or extensions that are not grouped together
      2. 2834587Domain d1s5tb_: 1s5t B: [98572]
        mutant
        has additional insertions and/or extensions that are not grouped together
    3. Domains for 1s5v:
      1. 2834590Domain d1s5va_: 1s5v A: [98581]
        mutant
        has additional insertions and/or extensions that are not grouped together
      2. 2834591Domain d1s5vb_: 1s5v B: [98582]
        mutant
        has additional insertions and/or extensions that are not grouped together
    4. Domains for 1s5w:
      1. 2834588Domain d1s5wa_: 1s5w A: [98583]
        mutant
        has additional insertions and/or extensions that are not grouped together
      2. 2834589Domain d1s5wb_: 1s5w B: [98584]
        mutant
        has additional insertions and/or extensions that are not grouped together
    5. Domains for 1yxc:
      1. 2834596Domain d1yxca_: 1yxc A: [124183]
        automated match to d1dhpa_
        complexed with cl, k

        has additional insertions and/or extensions that are not grouped together
      2. 2834597Domain d1yxcb_: 1yxc B: [124184]
        automated match to d1dhpa_
        complexed with cl, k

        has additional insertions and/or extensions that are not grouped together
    6. Domains for 1yxd:
      1. 2834600Domain d1yxda_: 1yxd A: [124185]
        automated match to d1dhpa_
        complexed with cl, k, lys

        has additional insertions and/or extensions that are not grouped together
      2. 2834601Domain d1yxdb_: 1yxd B: [124186]
        automated match to d1dhpa_
        complexed with cl, k, lys

        has additional insertions and/or extensions that are not grouped together
    7. Domains for 2a6l:
      1. 2834604Domain d2a6la1: 2a6l A:1-292 [126285]
        complexed with k; mutant
        has additional insertions and/or extensions that are not grouped together
      2. 2834605Domain d2a6lb_: 2a6l B: [126286]
        automated match to d1dhpa_
        complexed with k; mutant

        has additional insertions and/or extensions that are not grouped together
    8. Domains for 2a6n:
      1. 2834598Domain d2a6na1: 2a6n A:1-292 [126289]
        complexed with k; mutant
        has additional insertions and/or extensions that are not grouped together
      2. 2834599Domain d2a6nb_: 2a6n B: [126290]
        automated match to d1dhpa_
        complexed with k; mutant

        has additional insertions and/or extensions that are not grouped together
    9. Domains for 2ats:
      1. 2834594Domain d2atsa_: 2ats A: [127306]
        automated match to d1dhpa_
        complexed with cl, dly, k

        has additional insertions and/or extensions that are not grouped together
      2. 2834595Domain d2atsb_: 2ats B: [127307]
        automated match to d1dhpa_
        complexed with cl, dly, k

        has additional insertions and/or extensions that are not grouped together
    10. Domains for 2ojp:
      1. 2834584Domain d2ojpa_: 2ojp A: [166718]
        automated match to d1dhpa_
        complexed with gol; mutant

        has additional insertions and/or extensions that are not grouped together
      2. 2834585Domain d2ojpb_: 2ojp B: [166719]
        automated match to d1dhpa_
        complexed with gol; mutant

        has additional insertions and/or extensions that are not grouped together
    11. Domains for 2pur:
      1. 2834582Domain d2pura_: 2pur A: [167275]
        automated match to d1dhpa_
        complexed with gol, k, po4; mutant

        has additional insertions and/or extensions that are not grouped together
      2. 2834583Domain d2purb_: 2pur B: [167276]
        automated match to d1dhpa_
        complexed with gol, k, po4; mutant

        has additional insertions and/or extensions that are not grouped together
    12. Domains for 3c0j:
      1. 2834614Domain d3c0ja_: 3c0j A: [172973]
        automated match to d1dhpa_
        complexed with gol, k, po4

        has additional insertions and/or extensions that are not grouped together
      2. 2834615Domain d3c0jb_: 3c0j B: [172974]
        automated match to d1dhpa_
        complexed with gol, k, po4

        has additional insertions and/or extensions that are not grouped together
    13. Domains for 3du0:
      1. 2834602Domain d3du0a_: 3du0 A: [174226]
        automated match to d1dhpa_
        complexed with cl, gol, k

        has additional insertions and/or extensions that are not grouped together
      2. 2834603Domain d3du0b_: 3du0 B: [174227]
        automated match to d1dhpa_
        complexed with cl, gol, k

        has additional insertions and/or extensions that are not grouped together
    14. Domains for 3i7q:
      1. 2834576Domain d3i7qa_: 3i7q A: [178133]
        automated match to d1dhpa_
        complexed with gol, k, po4; mutant

        has additional insertions and/or extensions that are not grouped together
      2. 2834577Domain d3i7qb_: 3i7q B: [178134]
        automated match to d1dhpa_
        complexed with gol, k, po4; mutant

        has additional insertions and/or extensions that are not grouped together
    15. Domains for 3ubs:
      1. 2834580Domain d3ubsa_: 3ubs A: [306648]
        automated match to d4eoua_
        complexed with gol, k

        has additional insertions and/or extensions that are not grouped together
      2. 2834581Domain d3ubsb_: 3ubs B: [306649]
        automated match to d4eoua_
        complexed with gol, k

        has additional insertions and/or extensions that are not grouped together
    16. Domains for 4eou:
      1. 2834578Domain d4eoua_: 4eou A: [192395]
        complexed with gol, k
        has additional insertions and/or extensions that are not grouped together
      2. 2834579Domain d4eoub_: 4eou B: [192396]
        complexed with gol, k
        has additional insertions and/or extensions that are not grouped together
    17. Domains for 6nva:
      1. 2834606Domain d6nvaa1: 6nva A:1-292 [365480]
        Other proteins in same PDB: d6nvaa2, d6nvab2, d6nvac2, d6nvad2, d6nvae2, d6nvaf2, d6nvag2, d6nvah2
        automated match to d2atsa_
        complexed with gol, na

        has additional insertions and/or extensions that are not grouped together
      2. 2834607Domain d6nvab1: 6nva B:1-292 [365444]
        Other proteins in same PDB: d6nvaa2, d6nvab2, d6nvac2, d6nvad2, d6nvae2, d6nvaf2, d6nvag2, d6nvah2
        automated match to d2atsa_
        complexed with gol, na

        has additional insertions and/or extensions that are not grouped together
      3. 2834608Domain d6nvac1: 6nva C:1-292 [365475]
        Other proteins in same PDB: d6nvaa2, d6nvab2, d6nvac2, d6nvad2, d6nvae2, d6nvaf2, d6nvag2, d6nvah2
        automated match to d2atsa_
        complexed with gol, na

        has additional insertions and/or extensions that are not grouped together
      4. 2834609Domain d6nvad1: 6nva D:1-292 [365442]
        Other proteins in same PDB: d6nvaa2, d6nvab2, d6nvac2, d6nvad2, d6nvae2, d6nvaf2, d6nvag2, d6nvah2
        automated match to d2atsa_
        complexed with gol, na

        has additional insertions and/or extensions that are not grouped together
      5. 2834610Domain d6nvae1: 6nva E:1-292 [365436]
        Other proteins in same PDB: d6nvaa2, d6nvab2, d6nvac2, d6nvad2, d6nvae2, d6nvaf2, d6nvag2, d6nvah2
        automated match to d2atsa_
        complexed with gol, na

        has additional insertions and/or extensions that are not grouped together
      6. 2834611Domain d6nvaf1: 6nva F:1-292 [365460]
        Other proteins in same PDB: d6nvaa2, d6nvab2, d6nvac2, d6nvad2, d6nvae2, d6nvaf2, d6nvag2, d6nvah2
        automated match to d2atsa_
        complexed with gol, na

        has additional insertions and/or extensions that are not grouped together
      7. 2834612Domain d6nvag1: 6nva G:1-292 [365453]
        Other proteins in same PDB: d6nvaa2, d6nvab2, d6nvac2, d6nvad2, d6nvae2, d6nvaf2, d6nvag2, d6nvah2
        automated match to d2atsa_
        complexed with gol, na

        has additional insertions and/or extensions that are not grouped together
      8. 2834613Domain d6nvah1: 6nva H:1-292 [365464]
        Other proteins in same PDB: d6nvaa2, d6nvab2, d6nvac2, d6nvad2, d6nvae2, d6nvaf2, d6nvag2, d6nvah2
        automated match to d2atsa_
        complexed with gol, na

        has additional insertions and/or extensions that are not grouped together
  8. 2834616Escherichia coli [TaxId:585034] [323806] (2 PDB entries)
    1. Domains for 5t25:
      1. 2834617Domain d5t25a1: 5t25 A:1-292 [330476]
        Other proteins in same PDB: d5t25a2
        automated match to d3du0a_
        complexed with lys, na

        has additional insertions and/or extensions that are not grouped together
      2. 2834618Domain d5t25b_: 5t25 B: [330478]
        Other proteins in same PDB: d5t25a2
        automated match to d3du0a_
        complexed with lys, na

        has additional insertions and/or extensions that are not grouped together
    2. Domains for 5t26:
      1. 2834619Domain d5t26a1: 5t26 A:1-292 [323869]
        Other proteins in same PDB: d5t26a2, d5t26b2
        automated match to d2atsa_
        complexed with 74p, gol, na, tla

        has additional insertions and/or extensions that are not grouped together
      2. 2834620Domain d5t26b1: 5t26 B:1-292 [323807]
        Other proteins in same PDB: d5t26a2, d5t26b2
        automated match to d2atsa_
        complexed with 74p, gol, na, tla

        has additional insertions and/or extensions that are not grouped together
  9. 2834621Methanocaldococcus jannaschii [TaxId:243232] [188258] (1 PDB entry)
    • Domains for 2yxg:
      1. 2834622Domain d2yxga_: 2yxg A: [170909]
        automated match to d1o5ka_
        has additional insertions and/or extensions that are not grouped together
      2. 2834623Domain d2yxgb_: 2yxg B: [170910]
        automated match to d1o5ka_
        has additional insertions and/or extensions that are not grouped together
      3. 2834624Domain d2yxgc_: 2yxg C: [170911]
        automated match to d1o5ka_
        has additional insertions and/or extensions that are not grouped together
      4. 2834625Domain d2yxgd_: 2yxg D: [170912]
        automated match to d1o5ka_
        has additional insertions and/or extensions that are not grouped together
  10. 2834626Mycobacterium tuberculosis [TaxId:1773] [141831] (2 PDB entries)
    Uniprot P63945 5-300
    1. Domains for 1xxx:
      1. 2834627Domain d1xxxa1: 1xxx A:5-300 [122433]
        complexed with cl, dtt, mg
        has additional insertions and/or extensions that are not grouped together
      2. 2834628Domain d1xxxb_: 1xxx B: [122434]
        automated match to d1o5ka_
        complexed with cl, dtt, mg

        has additional insertions and/or extensions that are not grouped together
      3. 2834629Domain d1xxxc_: 1xxx C: [122435]
        automated match to d1o5ka_
        complexed with cl, dtt, mg

        has additional insertions and/or extensions that are not grouped together
      4. 2834630Domain d1xxxd_: 1xxx D: [122436]
        automated match to d1o5ka_
        complexed with cl, dtt, mg

        has additional insertions and/or extensions that are not grouped together
      5. 2834631Domain d1xxxe_: 1xxx E: [122437]
        automated match to d1o5ka_
        complexed with cl, dtt, mg

        has additional insertions and/or extensions that are not grouped together
      6. 2834632Domain d1xxxf_: 1xxx F: [122438]
        automated match to d1o5ka_
        complexed with cl, dtt, mg

        has additional insertions and/or extensions that are not grouped together
      7. 2834633Domain d1xxxg_: 1xxx G: [122439]
        automated match to d1o5ka_
        complexed with cl, dtt, mg

        has additional insertions and/or extensions that are not grouped together
      8. 2834634Domain d1xxxh_: 1xxx H: [122440]
        automated match to d1o5ka_
        complexed with cl, dtt, mg

        has additional insertions and/or extensions that are not grouped together
    2. Domain for 5j5d:
      • 2834635Domain d5j5da_: 5j5d A: [321363]
        automated match to d3l21a_
        complexed with 6gt, na

        has additional insertions and/or extensions that are not grouped together
  11. 2834636Pseudomonas aeruginosa [TaxId:287] [189992] (1 PDB entry)
    • Domains for 3s8h:
      1. 2834637Domain d3s8ha_: 3s8h A: [185311]
        automated match to d1dhpa_
        complexed with 3oh

        has additional insertions and/or extensions that are not grouped together
      2. 2834638Domain d3s8hb_: 3s8h B: [185312]
        automated match to d1dhpa_
        complexed with 3oh

        has additional insertions and/or extensions that are not grouped together
  12. 2834639Pseudomonas aeruginosa, PA01 [TaxId:208964] [189575] (2 PDB entries)
    1. Domains for 3ps7:
      1. 2834642Domain d3ps7a_: 3ps7 A: [183949]
        automated match to d1dhpa_
        complexed with pgo

        has additional insertions and/or extensions that are not grouped together
      2. 2834643Domain d3ps7b_: 3ps7 B: [183950]
        automated match to d1dhpa_
        complexed with pgo

        has additional insertions and/or extensions that are not grouped together
    2. Domains for 3puo:
      1. 2834640Domain d3puoa_: 3puo A: [183980]
        automated match to d1dhpa_
        complexed with gol, lys

        has additional insertions and/or extensions that are not grouped together
      2. 2834641Domain d3puob_: 3puo B: [183981]
        automated match to d1dhpa_
        complexed with gol, lys

        has additional insertions and/or extensions that are not grouped together
  13. 2834644Thermotoga maritima [TaxId:2336] [102090] (1 PDB entry)
    • Domains for 1o5k:
      1. 2834645Domain d1o5ka1: 1o5k A:1-294 [92504]
        Other proteins in same PDB: d1o5ka2, d1o5kb2
        structural genomics
        complexed with ca

        has additional insertions and/or extensions that are not grouped together
      2. 2834646Domain d1o5kb1: 1o5k B:1-294 [92505]
        Other proteins in same PDB: d1o5ka2, d1o5kb2
        structural genomics
        complexed with ca

        has additional insertions and/or extensions that are not grouped together

More info for Protein Dihydrodipicolinate synthase from c.1.10.1: Class I aldolase

Timeline for Protein Dihydrodipicolinate synthase from c.1.10.1: Class I aldolase: