SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family b.29.1.1: Legume lectins

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2042196Fold b.29: Concanavalin A-like lectins/glucanases [49898] (1 superfamily)
    sandwich; 12-14 strands in 2 sheets; complex topology
  4. 2042197Superfamily b.29.1: Concanavalin A-like lectins/glucanases [49899] (26 families) (S)
  5. 2042198Family b.29.1.1: Legume lectins [49900] (5 protein domains)

Protein Domains:

  1. 2042199alpha-Amylase inhibitor [49923] (1 species)
  2. 2042202Concanavalin A [49901] (4 species)
    natural circle permutation: the "old" N- and C-termini are linked with a peptide bond, whereas the "new" ones correspond to a cleaved loop
    1. 2042203Species Brazilian jackbean (Canavalia brasiliensis) [TaxId:61861] [49903] (6 PDB entries)
    2. 2042214Species Canavalia cathartica [TaxId:28958] [224859] (1 PDB entry)
    3. 2042218Species Canavalia virosa [TaxId:28958] [186936] (3 PDB entries)
    4. 2042222Species Jack bean (Canavalia ensiformis) [TaxId:3823] [49902] (57 PDB entries)
      Uniprot P81461
  3. 2042364Legume lectin [49904] (23 species)
    1. 2042365Species Black locust (Robinia pseudoacacia) [TaxId:35938] [63730] (2 PDB entries)
    2. 2042368Species Bloodwood tree (Pterocarpus angolensis) [TaxId:182271] [82032] (9 PDB entries)
    3. 2042387Species Cockspur coral tree (Erythrina crista-galli) [TaxId:49817] [74903] (5 PDB entries)
      Uniprot Q6YD91
    4. 2042400Species Common lentil (Lens culinaris) [TaxId:3864] [49906] (4 PDB entries)
      two-chain protein resulted from a single-chain precursor
    5. 2042408Species Coral tree (Erythrina corallodendron) [TaxId:3843] [49908] (8 PDB entries)
      Uniprot P16404
    6. 2042423Species Cratylia mollis, isoform 1 [TaxId:252530] [101633] (1 PDB entry)
      natural circle permutation resulting from a post-translational modification of precursor
    7. 2042425Species Duke (Dioclea guianensis) [TaxId:99571] [63729] (2 PDB entries)
      natural circle permutation resulting from a post-translational modification of precursor
    8. 2042429Species Field bean (Dolichos lablab), Fril [TaxId:35936] [49914] (1 PDB entry)
      a legume lectin that delays hematopoietic progenitor maturation
    9. 2042434Species Furze (Ulex europaeus), UEA-I [TaxId:3902] [49917] (2 PDB entries)
    10. 2042441Species Furze (Ulex europaeus), UEA-II [TaxId:3902] [49918] (5 PDB entries)
    11. 2042460Species Griffonia simplicifolia, lectin I-b4 [TaxId:3850] [69235] (2 PDB entries)
    12. 2042464Species Hairy vetch (Vicia villosa), isolectin b4 [TaxId:3911] [82033] (1 PDB entry)
    13. 2042469Species Horse gram (Dolichos biflorus), different isoforms [TaxId:3840] [49915] (5 PDB entries)
    14. 2042493Species Lathyrus ochrus, isolectin I [TaxId:3858] [49910] (7 PDB entries)
    15. 2042516Species Lathyrus ochrus, isolectin II [TaxId:3858] [49911] (2 PDB entries)
    16. 2042521Species Maackia amurensis, leukoagglutinin [TaxId:37501] [49919] (1 PDB entry)
    17. 2042524Species Mucana (Dioclea grandiflora) [TaxId:3837] [49916] (1 PDB entry)
      natural circle permutation resulting from a post-translational modification of precursor
    18. 2042527Species Pea (Pisum sativum) [TaxId:3888] [49905] (6 PDB entries)
      two-chain protein resulted from a single-chain precursor
    19. 2042540Species Peanut (Arachis hypogaea) [TaxId:3818] [49912] (24 PDB entries)
      Uniprot P02872 24-255
    20. 2042651Species Soybean (Glycine max) [TaxId:3847] [49913] (5 PDB entries)
    21. 2042657Species West-central african legume (Griffonia simplicifolia) [TaxId:3850] [49907] (3 PDB entries)
    22. 2042661Species Winged bean (Psophocarpus tetragonolobus), acidic lectin [TaxId:3891] [63728] (2 PDB entries)
    23. 2042672Species Winged bean (Psophocarpus tetragonolobus), basic agglutinin [TaxId:3891] [49909] (13 PDB entries)
  4. 2042723Phytohemagglutinin-L, PHA-L, also arcelin [49920] (2 species)
    single-chain subunit has "generic" topology
    1. 2042724Species French bean (Phaseolus vulgaris) [TaxId:3885] [49921] (4 PDB entries)
    2. 2042736Species French bean (Phaseolus vulgaris), G02771, arcelin-5a [TaxId:3885] [49922] (1 PDB entry)
  5. 2042739automated matches [190035] (24 species)
    not a true protein
    1. 2042740Species Bloodwood tree (Pterocarpus angolensis) [TaxId:182271] [186754] (21 PDB entries)
    2. 2042783Species Butea monosperma [TaxId:56060] [189858] (2 PDB entries)
    3. 2042790Species Camptosema pedicellatum [TaxId:232302] [194699] (1 PDB entry)
    4. 2042792Species Canavalia boliviana [TaxId:232300] [238384] (3 PDB entries)
    5. 2042802Species Canavalia gladiata [TaxId:3824] [187610] (5 PDB entries)
    6. 2042820Species Canavalia grandiflora [TaxId:232301] [256991] (1 PDB entry)
    7. 2042822Species Canavalia lineata [TaxId:28957] [193321] (5 PDB entries)
    8. 2042830Species Canavalia maritima [TaxId:3825] [187574] (6 PDB entries)
    9. 2042846Species Coral tree (Erythrina corallodendron) [TaxId:3843] [189686] (3 PDB entries)
    10. 2042850Species Cratylia argentea [TaxId:83131] [187602] (2 PDB entries)
    11. 2042859Species Cymbosema roseum [TaxId:202239] [189292] (2 PDB entries)
    12. 2042865Species Dioclea rostrata [TaxId:192416] [188569] (1 PDB entry)
    13. 2042867Species Dioclea sclerocarpa [TaxId:1176036] [268405] (1 PDB entry)
    14. 2042869Species Dioclea violacea [TaxId:192415] [187744] (2 PDB entries)
    15. 2042875Species Dioclea virgata [TaxId:167618] [189798] (2 PDB entries)
    16. 2042878Species Dioclea wilsonii [TaxId:763456] [189735] (1 PDB entry)
    17. 2042880Species Duke (Dioclea guianensis) [TaxId:99571] [188246] (2 PDB entries)
    18. 2042883Species French bean (Phaseolus vulgaris) [TaxId:3885] [238518] (3 PDB entries)
    19. 2042890Species Mucana (Dioclea grandiflora) [TaxId:3837] [188247] (3 PDB entries)
    20. 2042900Species Platypodium elegans [TaxId:115002] [189870] (2 PDB entries)
    21. 2042905Species Winged bean (Psophocarpus tetragonolobus) [TaxId:3891] [187047] (1 PDB entry)
    22. 2270505Species Centrolobium tomentosum [TaxId:500182] [313810] (2 PDB entries)
    23. 2281139Species Canavalia cathartica [TaxId:28958] [324440] (1 PDB entry)
    24. 2286568Species Dioclea reflexa [TaxId:1048258] [329869] (1 PDB entry)

More info for Family b.29.1.1: Legume lectins

Timeline for Family b.29.1.1: Legume lectins: