Class a: All alpha proteins [46456] (289 folds) |
Fold a.24: Four-helical up-and-down bundle [47161] (28 superfamilies) core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down |
Superfamily a.24.7: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47212] (1 family) automatically mapped to Pfam PF08771 |
Family a.24.7.1: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47213] (2 proteins) |
Protein mTOR FKBP12–rapamycin-binding (FRB) domain [47214] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [47215] (11 PDB entries) |
Domain d1auea_: 1aue A: [16615] |
Domain d1aueb_: 1aue B: [16616] |
Domain d1fapb_: 1fap B: [16618] Other proteins in same PDB: d1fapa_ complexed with rap |
Domain d1nsgb_: 1nsg B: [16613] Other proteins in same PDB: d1nsga_ complexed with rad |
Domain d2fapb_: 2fap B: [16614] Other proteins in same PDB: d2fapa_ complexed with rad |
Domain d2gaqa_: 2gaq A: [134893] automated match to d1fapb_ |
Domain d3fapb_: 3fap B: [16612] Other proteins in same PDB: d3fapa_ complexed with ard |
Domain d4drhb1: 4drh B:2025-2112 [201732] Other proteins in same PDB: d4drha_, d4drhb2, d4drhd_, d4drhe2 automated match to d4drhe_ complexed with rap, so4 |
Domain d4drhe1: 4drh E:2025-2112 [193177] Other proteins in same PDB: d4drha_, d4drhb2, d4drhd_, d4drhe2 automated match to d1aueb_ complexed with rap, so4 |
Domain d4drib1: 4dri B:2025-2112 [219969] Other proteins in same PDB: d4dria_, d4drib2 automated match to d4drhe_ complexed with rap |
Domain d4drjb1: 4drj B:2025-2114 [201734] Other proteins in same PDB: d4drja_, d4drjb2 automated match to d4drhe_ complexed with rap, so4 |
Domain d4fapb_: 4fap B: [16617] Other proteins in same PDB: d4fapa_ complexed with ard |
Domain d4jspa2: 4jsp A:2022-2113 [345313] Other proteins in same PDB: d4jspa1 complexed with ags, mg |
Domain d4jspa3: 4jsp A:1385-2001 [345314] Other proteins in same PDB: d4jspa1 complexed with ags, mg |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.24.7.1 mTOR FKBP12–rapamycin-binding (FRB) domain: