SCOP 1.69: Domain d1f3mc_: 1f3m C:

Lineage for d1f3mc_ (1f3m C:)

1. Root: SCOP 1.69

2. Class d: Alpha and beta proteins (a+b) [53931] (279 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (53 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein pak1 [56146] (1 species)
   OPK group; PAK/STE20 subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56147] (1 PDB entry)

8. Domain d1f3mc_: 1f3m C: [41677]
   Other proteins in same PDB: d1f3ma_, d1f3mb_

Details for d1f3mc_

PDB Entry: 1f3m, 2.3 Å

PDB Description: crystal structure of human serine/threonine kinase pak1

SCOP Domain Sequences for d1f3mc_:

Sequence, based on SEQRES records:

>d1f3mc_ d.144.1.7 (C:) pak1 {Human (Homo sapiens)}
sdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevairqmnlqqqpk
keliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaa
vcreclqaleflhsnqvihrdiksdnillgmdgsvkltdfgfcaqitpeqskrstmvgtp
ywmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpe
klsaifrdflnrcldmdvekrgsakellqhqflkiakplssltpliaaakeatk

Sequence, based on observed residues (ATOM records):

>d1f3mc_ d.144.1.7 (C:) pak1 {Human (Homo sapiens)}
sdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevairqmnlqqqpk
keliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaa
vcreclqaleflhsnqvihrdiksdnillgmdgsvkltdfgfcaqittmvgtpywmapev
vtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpeklsaifr
dflnrcldmdvekrgsakellqhqflkiakplssltpliaaakeatk

Timeline for d1f3mc_:

• d1f3mc_ first appeared (with stable ids) in SCOP 1.55
  
• d1f3mc_ appears in SCOP 1.67
  
• d1f3mc_ appears in SCOP 1.71
  
• d1f3mc_ appears in the current release, SCOPe 2.08