SCOPe 2.07: Domain d7mk8a_: 7mk8 A:

Lineage for d7mk8a_ (7mk8 A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.1: Cytochrome P450 [48265] (23 proteins)

6. Protein automated matches [190068] (13 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [189507] (93 PDB entries)

8. Domain d7mk8a_: 7mk8 A: [405711]
   automated match to d1w0ea_
   complexed with dtv, hem, so4; mutant

Details for d7mk8a_

PDB Entry: 7mk8, 2.15 Å

PDB Description: crystal structure of a surface mutant of human fetal-specific cyp3a7 bound to dithiothreitol

PDB Compounds: (A:) Isoform 2 of Cytochrome P450 3A7

SCOPe Domain Sequences for d7mk8a_:

Sequence, based on SEQRES records:

>d7mk8a_ a.104.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ygtrthglfkklgipgptplpflgnalsfrkgywtfdmecykkygkvwgiydgqqpmlai
tdpdmiktvlvkecysvftnrrpfgpvgfmknaisiaedeewkrirsllsptftsgklke
mvpiiaqygdvlvrnlrreaetgkpvtlkhvfgaysmdvitstsfgvsidslnnpqdpfv
entkkllrfnpldpfvlsikvfpfltpilealnitvfprevisfltksvkqikegrlket
qkhrvdflqlmidsqnskdsethkalsdlelmaqsiififagyettssvlsfiiyelath
pdvqqkvqkeidtvlpnkapptydtvlqleyldmvvnetlrlfpvamrlervckkdvein
gmfipkgvvvmipsyvlhhdpkywtepekflperfsaanadnidpyiytpfgsgprncig
mrfalvnmklalvrvlqnfsfkpcketqiplklrfggllltekpivlkaesrd

Sequence, based on observed residues (ATOM records):

>d7mk8a_ a.104.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ygtrthglfkklgipgptplpflgnalsfrkgywtfdmecykkygkvwgiydgqqpmlai
tdpdmiktvlvkecysvftnrrpfgpvgfmknaisiaedeewkrirsllsptftsgklke
mvpiiaqygdvlvrnlrreaetgkpvtlkhvfgaysmdvitstsfgvsidslnnpqdpfv
entkkllrfnpldpfvlsikvfpfltpilealnitvfprevisfltksvkqikegrlkvd
flqlmidsqnthkalsdlelmaqsiififagyettssvlsfiiyelathpdvqqkvqkei
dtvlpnkapptydtvlqleyldmvvnetlrlfpvamrlervckkdveingmfipkgvvvm
ipsyvlhhdpkywtepekflperfsaanadnidpyiytpfgsgprncigmrfalvnmkla
lvrvlqnfsfkpcketqiplklrfggllltekpivlkaesrd

Timeline for d7mk8a_:

• d7mk8a_ is new in SCOPe 2.07-stable
  
• d7mk8a_ appears in the current release, SCOPe 2.08