SCOP 1.63: Domain d1grt_3: 1grt 364-478

Lineage for d1grt_3 (1grt 364-478)

1. Root: SCOP 1.63

2. Class d: Alpha and beta proteins (a+b) [53931] (224 folds)

3. Fold d.87: CO dehydrogenase flavoprotein C-domain-like [55423] (2 superfamilies)
   core: beta(3,4)-alpha(3); alpha+beta sandwich

4. Superfamily d.87.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55424] (1 family)
   both first two domains are of same beta/beta/alpha fold

5. Family d.87.1.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55425] (10 proteins)

6. Protein Glutathione reductase [55426] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55427] (17 PDB entries)

8. Domain d1grt_3: 1grt 364-478 [40165]
   Other proteins in same PDB: d1grt_1, d1grt_2
   complexed with fad; mutant

Details for d1grt_3

PDB Entry: 1grt, 2.3 Å

PDB Description: human glutathione reductase a34e/r37w mutant

SCOP Domain Sequences for d1grt_3:

Sequence; same for both SEQRES and ATOM records:

>d1grt_3 d.87.1.1 (364-478) Glutathione reductase {Human (Homo sapiens)}
ynniptvvfshppigtvgltedeaihkygienvktystsftpmyhavtkrktkcvmkmvc
ankeekvvgihmqglgcdemlqgfavavkmgatkadfdntvaihptsseelvtlr

Timeline for d1grt_3:

• d1grt_3 first appeared (with stable ids) in SCOP 1.55
  
• d1grt_3 appears in SCOP 1.61
  
• d1grt_3 appears in SCOP 1.65
  
• d1grt_3 appears in the current release, SCOPe 2.08, called d1grta3