SCOPe 2.07: Domain d6ye3c_: 6ye3 C:

Lineage for d6ye3c_ (6ye3 C:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.26: 4-helical cytokines [47265] (1 superfamily)
   core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections

4. Superfamily a.26.1: 4-helical cytokines [47266] (4 families)
   there are two different topoisomers of this fold with different entanglements of the two crossover connections

5. Family a.26.1.2: Short-chain cytokines [47286] (14 proteins)

6. Protein Interleukin-2 (IL-2) [47301] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47302] (19 PDB entries)

8. Domain d6ye3c_: 6ye3 C: [398023]
   Other proteins in same PDB: d6ye3b1, d6ye3b2, d6ye3e1, d6ye3e2, d6ye3h1, d6ye3h2
   automated match to d1irla_

Details for d6ye3c_

PDB Entry: 6ye3, 2.89 Å

PDB Description: il-2 in complex with a fab fragment from ufka-20

PDB Compounds: (C:) interleukin-2

SCOPe Domain Sequences for d6ye3c_:

Sequence; same for both SEQRES and ATOM records:

>d6ye3c_ a.26.1.2 (C:) Interleukin-2 (IL-2) {Human (Homo sapiens) [TaxId: 9606]}
tssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleee
lkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnrwi
tfcqsiistlt

Timeline for d6ye3c_:

• d6ye3c_ is new in SCOPe 2.07-stable
  
• d6ye3c_ appears in the current release, SCOPe 2.08