SCOPe 2.07: Domain d7c2vb1: 7c2v B:162-459

Lineage for d7c2vb1 (7c2v B:162-459)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d7c2vb1: 7c2v B:162-459 [394415]
   Other proteins in same PDB: d7c2vb2
   automated match to d2oicd_
   complexed with fj0

Details for d7c2vb1

PDB Entry: 7c2v, 2.44 Å

PDB Description: crystal structure of irak4 kinase in complex with the inhibitor ca- 4948

PDB Compounds: (B:) interleukin-1 receptor-associated kinase 4

SCOPe Domain Sequences for d7c2vb1:

Sequence, based on SEQRES records:

>d7c2vb1 d.144.1.0 (B:162-459) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaamvdi
tteelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtp
plswhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekfaq
tvmtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldike
eiedeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemta

Sequence, based on observed residues (ATOM records):

>d7c2vb1 d.144.1.0 (B:162-459) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklakqqfd
qeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtpplswhmrcki
aqgaanginflhenhhihrdiksanilldeaftakisdfglarastvmtsrivgttayma
pealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidk
kmndadstsveamysvasqclhekknkrpdikkvqqllqemta

Timeline for d7c2vb1:

• d7c2vb1 is new in SCOPe 2.07-stable
  
• d7c2vb1 appears in the current release, SCOPe 2.08