SCOPe 2.07: Domain d7b44a_: 7b44 A:

Lineage for d7b44a_ (7b44 A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (892 PDB entries)

8. Domain d7b44a_: 7b44 A: [394339]
   automated match to d2g15a_
   complexed with dms, so4, svt

Details for d7b44a_

PDB Entry: 7b44, 1.76 Å

PDB Description: crystal structure of c-met bound by compound s1

PDB Compounds: (A:) Hepatocyte growth factor receptor

SCOPe Domain Sequences for d7b44a_:

Sequence, based on SEQRES records:

>d7b44a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lsalnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcavkslnr
itdigevsqfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirneth
nptvkdligfglqvakgmkylaskkfvhrdlaarncmldekftvkvadfglardmydkey
ysvhnktgaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditv
yllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfig

Sequence, based on observed residues (ATOM records):

>d7b44a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lsalnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcavkslnr
itdigevsqfltegiimkdfshpnvlsllgiclgsplvvlpymkhgdlrnfirnethnpt
vkdligfglqvakgmkylaskkfvhrdlaarncmldekftvkvadfglardmydkeyysv
hpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditvyllqgrrllq
peycpdplyevmlkcwhpkaemrpsfselvsrisaifstfig

Timeline for d7b44a_:

• d7b44a_ is new in SCOPe 2.07-stable
  
• d7b44a_ appears in the current release, SCOPe 2.08