SCOPe 2.07: Domain d6yt1a_: 6yt1 A:

Lineage for d6yt1a_ (6yt1 A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidylate kinase [52563] (5 species)

7. Species Mycobacterium tuberculosis [TaxId:83332] [346929] (5 PDB entries)

8. Domain d6yt1a_: 6yt1 A: [393778]
   automated match to d1gsia_
   complexed with cit, pk5

Details for d6yt1a_

PDB Entry: 6yt1, 1.9 Å

PDB Description: mtb tmk crystal structure in complex with compound 26

PDB Compounds: (A:) thymidylate kinase

SCOPe Domain Sequences for d6yt1a_:

Sequence, based on SEQRES records:

>d6yt1a_ c.37.1.1 (A:) Thymidylate kinase {Mycobacterium tuberculosis [TaxId: 83332]}
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsaelagersrgraqrdpgrardnyerdaelqqrtgavya
elaaqgwggrwlvvgadvdpgrlaatlapp

Sequence, based on observed residues (ATOM records):

>d6yt1a_ c.37.1.1 (A:) Thymidylate kinase {Mycobacterium tuberculosis [TaxId: 83332]}
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsrdnyerdaelqqrtgavyaelaaqgwggrwlvvgadvd
pgrlaatlapp

Timeline for d6yt1a_:

• d6yt1a_ is new in SCOPe 2.07-stable
  
• d6yt1a_ appears in the current release, SCOPe 2.08