SCOPe 2.07: Domain d6yi8b_: 6yi8 B:

Lineage for d6yi8b_ (6yi8 B:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (892 PDB entries)

8. Domain d6yi8b_: 6yi8 B: [393682]
   automated match to d4v04b_
   complexed with fgf, so4

Details for d6yi8b_

PDB Entry: 6yi8, 2.13 Å

PDB Description: human fgfr4 kinase domain (447-753) in complex with roblitinib

PDB Compounds: (B:) Fibroblast growth factor receptor 4

SCOPe Domain Sequences for d6yi8b_:

Sequence, based on SEQRES records:

>d6yi8b_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sldlpldplwefprdrlvlgkplgegcfgqvvraeafgmdparpdqastvavkmlkdnas
dkdladlvsemevmkligrhkniinllgvctqegplyvivecaakgnlreflrarrppgp
dlspdgprssegplsfpvlvscayqvargmqylesrkcihrdlaarnvlvtednvmkiad
fglargvhhidyykktsngrlpvkwmapealfdrvythqsdvwsfgillweiftlggspy
pgipveelfsllreghrmdrpphcppelyglmrecwhaapsqrptfkqlvealdkvllav
se

Sequence, based on observed residues (ATOM records):

>d6yi8b_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sldlpldplwefprdrlvlgkplgegcfgqvvraeafgmdparpdqastvavkmlkdnas
dkdladlvsemevmkligrhkniinllgvctqegplyvivecaakgnlreflrarrpppl
sfpvlvscayqvargmqylesrkcihrdlaarnvlvtednvmkiadfglpvkwmapealf
drvythqsdvwsfgillweiftlggspypgipveelfsllreghrmdrpphcppelyglm
recwhaapsqrptfkqlvealdkvllavse

Timeline for d6yi8b_:

• d6yi8b_ is new in SCOPe 2.07-stable
  
• d6yi8b_ appears in the current release, SCOPe 2.08