SCOPe 2.07: Domain d6vpma1: 6vpm A:7-389

Lineage for d6vpma1 (6vpm A:7-389)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d6vpma1: 6vpm A:7-389 [392798]
   Other proteins in same PDB: d6vpma2, d6vpmb2
   automated match to d3dpka_
   complexed with amp, mg, mla, r74

Details for d6vpma1

PDB Entry: 6vpm, 1.58 Å

PDB Description: tpx2 residues 7-20 fused to aurora a residues 116-389 with c290 disulfide bonded to compound 8-34, and in complex with amp-pnp

PDB Compounds: (A:) TPX2 fragment - Aurora A kinase domain fusion

SCOPe Domain Sequences for d6vpma1:

Sequence, based on SEQRES records:

>d6vpma1 d.144.1.0 (A:7-389) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sysydapsdfinfsskqkneeskkrqwaledfeigrplgkgkfgnvylarekqskfilal
kvlfkaqlekagvehqlrreveiqshlrhpnilrlygyfhdatrvylileyaplgtvyre
lqklskfdeqrtatyitelanalsychskrvihrdikpenlllgsagelkiadfgwsvha
pssrrttlcgtldylppemiegrmhdekvdlwslgvlcyeflvgkppfeantyqetykri
srveftfpdfvtegardlisrllkhnpsqrpmlrevlehpwitanssk

Sequence, based on observed residues (ATOM records):

>d6vpma1 d.144.1.0 (A:7-389) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sysydapsdfinfsskrqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaql
ekagvehqlrreveiqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfd
eqrtatyitelanalsychskrvihrdikpenlllgsagelkiadfgwsvhapttlcgtl
dylppemiegrmhdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvt
egardlisrllkhnpsqrpmlrevlehpwitanssk

Timeline for d6vpma1:

• d6vpma1 is new in SCOPe 2.07-stable
  
• d6vpma1 appears in the current release, SCOPe 2.08