SCOPe 2.07: Domain d7c2qa_: 7c2q A:

Lineage for d7c2qa_ (7c2q A:)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (5 proteins)

6. Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (8 species)
   contains an extra alpha-helical domain

7. Species Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049] [385979] (34 PDB entries)

8. Domain d7c2qa_: 7c2q A: [389812]
   automated match to d2z9jb_

Details for d7c2qa_

PDB Entry: 7c2q, 1.93 Å

PDB Description: the crystal structure of covid-19 main protease in the apo state

PDB Compounds: (A:) 3C-like proteinase

SCOPe Domain Sequences for d7c2qa_:

Sequence, based on SEQRES records:

>d7c2qa_ b.47.1.4 (A:) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {Severe acute respiratory syndrome coronavirus 2 [TaxId: 2697049]}
frkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedllirks
nhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlacyngsp
sgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegnfy
gpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamkynyepl
tqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvvr

Sequence, based on observed residues (ATOM records):

>d7c2qa_ b.47.1.4 (A:) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {Severe acute respiratory syndrome coronavirus 2 [TaxId: 2697049]}
frkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedllirks
nhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlacyngsp
sgvyqcamrpnftikgsgscgsvgfnidydcvsfcymhhmelptgvhagtdlegnfygpf
vdrqtaqaagtdttitvnvlawlyaavgdrwflnrftttlndfnlvamkynyepltqdhv
dilgplsaqtgiavldmcaslkellqngmngrtsalledeftpfdvvr

Timeline for d7c2qa_:

• d7c2qa_ is new in SCOPe 2.07-stable
  
• d7c2qa_ appears in the current release, SCOPe 2.08