SCOPe 2.07: Domain d6vkoc1: 6vko C:664-796

Lineage for d6vkoc1 (6vko C:664-796)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.41: Domain of poly(ADP-ribose) polymerase [47586] (1 superfamily)
   core: 4 helices: bundle; unusual topology

4. Superfamily a.41.1: Domain of poly(ADP-ribose) polymerase [47587] (2 families)
   duplication: consists of 2 helix-loop-helix structural repeats
   automatically mapped to Pfam PF02877

5. Family a.41.1.0: automated matches [227223] (1 protein)
   not a true family

6. Protein automated matches [226964] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225405] (61 PDB entries)

8. Domain d6vkoc1: 6vko C:664-796 [388023]
   Other proteins in same PDB: d6vkoa2, d6vkob2, d6vkoc2, d6vkod2
   automated match to d4hhyd1
   complexed with l1s, so4

Details for d6vkoc1

PDB Entry: 6vko, 2.8 Å

PDB Description: crystal structure of human parp-1 cat domain bound to inhibitor uktt15

PDB Compounds: (C:) Poly [ADP-ribose] polymerase 1

SCOPe Domain Sequences for d6vkoc1:

Sequence, based on SEQRES records:

>d6vkoc1 a.41.1.0 (C:664-796) automated matches {Human (Homo sapiens) [TaxId: 9606]}
klpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqavsqg
ssdsqildlsnrfytliphdfgmkkppllnnadsvqakaemldnlldievaysllrggsd
dsskdpidvnyek

Sequence, based on observed residues (ATOM records):

>d6vkoc1 a.41.1.0 (C:664-796) automated matches {Human (Homo sapiens) [TaxId: 9606]}
klpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqavsqg
ssdsqildlsnrfytliphdfgmkkppllnnadsvqakaemldnlldievaysllrggid
vnyek

Timeline for d6vkoc1:

• d6vkoc1 is new in SCOPe 2.07-stable
  
• d6vkoc1 appears in the current release, SCOPe 2.08