Lineage for d6v6oc_ (6v6o C:)

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2586062Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2586063Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2586210Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2587580Protein EGF receptor tyrosine kinase, Erbb-1 [82795] (1 species)
    PTK group; EGFR subfamily; membrane spanning protein tyrosine kinase
  7. 2587581Species Human (Homo sapiens) [TaxId:9606] [82796] (129 PDB entries)
    Uniprot P00533 702-1018
  8. 2587646Domain d6v6oc_: 6v6o C: [384435]
    automated match to d4zseb_
    complexed with cl, qqm

Details for d6v6oc_

PDB Entry: 6v6o (more details), 2.1 Å

PDB Description: egfr(t790m/v948r) in complex with ln2380
PDB Compounds: (C:) Epidermal growth factor receptor

SCOPe Domain Sequences for d6v6oc_:

Sequence, based on SEQRES records: (download)

>d6v6oc_ d.144.1.7 (C:) EGF receptor tyrosine kinase, Erbb-1 {Human (Homo sapiens) [TaxId: 9606]}
qallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreatspkankeil
deayvmasvdnphvcrllgicltstvqlimqlmpfgclldyvrehkdnigsqyllnwcvq
iakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggkvpikw
malesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqppict
idvymimrkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsptdsnfyra
lmdeedmddvv

Sequence, based on observed residues (ATOM records): (download)

>d6v6oc_ d.144.1.7 (C:) EGF receptor tyrosine kinase, Erbb-1 {Human (Homo sapiens) [TaxId: 9606]}
qallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreatspkankeil
deayvmasvdnphvcrllgicltstvqlimqlmpfgclldyvrehkdnigsqyllnwcvq
iakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgvpikwmalesilhriyt
hqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqppictidvymimrkcwm
idadsrpkfreliiefskmardpqrylviqgdermhlpsptdsnfyralmdeedmvv

SCOPe Domain Coordinates for d6v6oc_:

Click to download the PDB-style file with coordinates for d6v6oc_.
(The format of our PDB-style files is described here.)

Timeline for d6v6oc_: