SCOPe 2.07: Domain d6pa4b_: 6pa4 B:

Lineage for d6pa4b_ (6pa4 B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.88: Glutaminase/Asparaginase [53773] (1 superfamily)
   consists of two non-similar alpha/beta domains, 3 layers (a/b/a) each
   Domain 1 has mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest; left-handed crossover connection between strands 4 and 5
   Domain 2 has parallel beta-sheet of 4 strands, order 1234

4. Superfamily c.88.1: Glutaminase/Asparaginase [53774] (2 families)

5. Family c.88.1.1: Glutaminase/Asparaginase [53775] (4 proteins)
   automatically mapped to Pfam PF00710

6. Protein Asparaginase type II [53776] (5 species)

7. Species Escherichia coli [TaxId:562] [53777] (40 PDB entries)

8. Domain d6pa4b_: 6pa4 B: [373668]
   Other proteins in same PDB: d6pa4c2, d6pa4d2
   automated match to d4ecaa_
   complexed with asp, gol; mutant

Details for d6pa4b_

PDB Entry: 6pa4, 1.85 Å

PDB Description: e. coli l-asparaginase ii double mutant (t89v,k162t) in complex with l-asp at ph 7.0

PDB Compounds: (B:) L-asparaginase 2

SCOPe Domain Sequences for d6pa4b_:

Sequence, based on SEQRES records:

>d6pa4b_ c.88.1.1 (B:) Asparaginase type II {Escherichia coli [TaxId: 562]}
lpnitilatggtiagggdsatksnytvgkvgvenlvnavpqlkdianvkgeqvvnigsqd
mndnvwltlakkintdcdktdgfvithgvdtmeetayfldltvkcdkpvvmvgamrpsts
msadgpfnlynavvtaadkasanrgvlvvmndtvldgrdvtttnttdvatfksvnygplg
yihngkidyqrtparkhtsdtpfdvsklnelpkvgivynyanasdlpakalvdagydgiv
sagvgngnlyksvfdtlataaktgtavvrssrvptgattqdaevddakygfvasgtlnpq
karvllqlaltqtkdpqqiqqifnqy

Sequence, based on observed residues (ATOM records):

>d6pa4b_ c.88.1.1 (B:) Asparaginase type II {Escherichia coli [TaxId: 562]}
lpnitilatggtivenlvnavpqlkdianvkgeqvvnigsqdmndnvwltlakkintdcd
ktdgfvithgvdtmeetayfldltvkcdkpvvmvgamrpstsmsadgpfnlynavvtaad
kasanrgvlvvmndtvldgrdvtttnttdvatfksvnygplgyihngkidyqrtparkht
sdtpfdvsklnelpkvgivynyanasdlpakalvdagydgivsagvgngnlyksvfdtla
taaktgtavvrssrvptgattqdaevddakygfvasgtlnpqkarvllqlaltqtkdpqq
iqqifnqy

Timeline for d6pa4b_:

• d6pa4b_ is new in SCOPe 2.07-stable
  
• d6pa4b_ appears in the current release, SCOPe 2.08