SCOPe 2.08: Domain d6pfma_: 6pfm A:

Lineage for d6pfma_ (6pfm A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (107 PDB entries)
   Uniprot P03372 307-551

8. Domain d6pfma_: 6pfm A: [371234]
   automated match to d3q95b_
   complexed with ogj

Details for d6pfma_

PDB Entry: 6pfm, 2.84 Å

PDB Description: crystal structure of gdc-0927 bound to estrogen receptor alpha

PDB Compounds: (A:) Estrogen receptor

SCOPe Domain Sequences for d6pfma_:

Sequence; same for both SEQRES and ATOM records:

>d6pfma_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpg
fvdltshdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifd
mllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtl
ihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkc

Timeline for d6pfma_:

• d6pfma_ first appeared in SCOPe 2.07