SCOPe 2.07: Domain d6r49a_: 6r49 A:

Lineage for d6r49a_ (6r49 A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d6r49a_: 6r49 A: [368782]
   automated match to d4tl0a_
   complexed with adp, jsb, mg

Details for d6r49a_

PDB Entry: 6r49, 2.21 Å

PDB Description: aurora-a in complex with shape-diverse fragment 39

PDB Compounds: (A:) Aurora kinase A

SCOPe Domain Sequences for d6r49a_:

Sequence, based on SEQRES records:

>d6r49a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqs
hlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsy
chskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlagtldylppemiegrmh
dekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkh
npsqrpmlrevlehpwitansskps

Sequence, based on observed residues (ATOM records):

>d6r49a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqs
hlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsy
chskrvihrdikpenlllgsagelkiadfgwsvhapssrgtldylppemiegrmhdekvd
lwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqr
pmlrevlehpwitansskps

Timeline for d6r49a_:

• d6r49a_ is new in SCOPe 2.07-stable
  
• d6r49a_ appears in the current release, SCOPe 2.08