Lineage for d6cxsa3 (6cxs A:276-599)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2434695Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2438500Superfamily c.1.8: (Trans)glycosidases [51445] (15 families) (S)
  5. 2441004Family c.1.8.0: automated matches [191314] (1 protein)
    not a true family
  6. 2441005Protein automated matches [190075] (125 species)
    not a true protein
  7. 2441194Species Clostridium perfringens [TaxId:195102] [267956] (2 PDB entries)
  8. 2441197Domain d6cxsa3: 6cxs A:276-599 [367777]
    Other proteins in same PDB: d6cxsa1, d6cxsa2, d6cxsa4, d6cxsb1, d6cxsb2, d6cxsb4, d6cxsd1, d6cxsd2
    automated match to d4jkla3
    complexed with fjv

Details for d6cxsa3

PDB Entry: 6cxs (more details), 2.8 Å

PDB Description: crystal structure of clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4- tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl) morpholine
PDB Compounds: (A:) beta-glucuronidase

SCOPe Domain Sequences for d6cxsa3:

Sequence, based on SEQRES records: (download)

>d6cxsa3 c.1.8.0 (A:276-599) automated matches {Clostridium perfringens [TaxId: 195102]}
vevkdgkflinnkpfyfkgfgkhedsyvngrgineainikdfnlmkwigansfrtshypy
seeimrladregivvidetpavglhlnfmatgfggdapkrdtwkeigtkeaherilrelv
srdknhpcvvmwsvanepdsdsegakeyfeplikltkeldpqkrpvtvvtylmstpdrck
vgdivdvlclnryygwyvaggdleeakrmledelkgweercpktpimfteygadtvaglh
dtvpvmfteeyqveyykanhevmdkcknfvgeqvwnfadfatsqgiirvqgnkkgiftre
rkpkmiahslrerwtnipefgykk

Sequence, based on observed residues (ATOM records): (download)

>d6cxsa3 c.1.8.0 (A:276-599) automated matches {Clostridium perfringens [TaxId: 195102]}
vevkdgkflinnkpfyfkgfgkhedsyvngrgineainikdfnlmkwigansfrtshypy
seeimrladregivvidetpavglhlnfmatgfpkrdtwkeigtkeaherilrelvsrdk
nhpcvvmwsvanepdsdsegakeyfeplikltkeldpqkrpvtvvtylmstpdrckvgdi
vdvlclnryygwyvaggdleeakrmledelkgweercpktpimfteygadtvaglhdtvp
vmfteeyqveyykanhevmdkcknfvgeqvwnfadfatsqgiirvqgnkkgiftrerkpk
miahslrerwtnipefgykk

SCOPe Domain Coordinates for d6cxsa3:

Click to download the PDB-style file with coordinates for d6cxsa3.
(The format of our PDB-style files is described here.)

Timeline for d6cxsa3: