SCOPe 2.07: Domain d6c1oa_: 6c1o A:

Lineage for d6c1oa_ (6c1o A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Fibroblast growth factor receptor 1 [56158] (1 species)
   PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56159] (47 PDB entries)

8. Domain d6c1oa_: 6c1o A: [362042]
   automated match to d4v04b_
   complexed with mk9, so4

Details for d6c1oa_

PDB Entry: 6c1o, 2.29 Å

PDB Description: fgfr1 kinase domain complexed with fiin-1

PDB Compounds: (A:) fibroblast growth factor receptor 1

SCOPe Domain Sequences for d6c1oa_:

Sequence, based on SEQRES records:

>d6c1oa_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdatek
dlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppgley
synpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfg
lardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypg
vpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivaltsn
qe

Sequence, based on observed residues (ATOM records):

>d6c1oa_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdatek
dlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppynps
hnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfgllpvk
wmapealfdriythqsdvwsfgvllweiftlggspypgvpveelfkllkeghrmdkpsnc
tnelymmmrdcwhavpsqrptfkqlvedldrivaltsnqe

Timeline for d6c1oa_:

• d6c1oa_ is new in SCOPe 2.07-stable
  
• d6c1oa_ appears in the current release, SCOPe 2.08