SCOPe 2.07: Domain d5z0sb_: 5z0s B:

Lineage for d5z0sb_ (5z0s B:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Fibroblast growth factor receptor 1 [56158] (1 species)
   PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56159] (47 PDB entries)

8. Domain d5z0sb_: 5z0s B: [361873]
   automated match to d4v04b_
   complexed with 960

Details for d5z0sb_

PDB Entry: 5z0s, 2.45 Å

PDB Description: crystal structure of fgfr1 kinase domain in complex with a novel inhibitor

PDB Compounds: (B:) fibroblast growth factor receptor 1

SCOPe Domain Sequences for d5z0sb_:

Sequence, based on SEQRES records:

>d5z0sb_ d.144.1.7 (B:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdatek
dlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppgley
synpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfg
lardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypg
vpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivalt

Sequence, based on observed residues (ATOM records):

>d5z0sb_ d.144.1.7 (B:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgegafgqvvlaeaiglpnrvtkvavkmlksdatekdlsd
lisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppeeqlsskd
lvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfglardhhidyykkttng
rlpvkwmapealfdriythqsdvwsfgvllweiftlggspypgvpveelfkllkeghrmd
kpsnctnelymmmrdcwhavpsqrptfkqlvedldrivalt

Timeline for d5z0sb_:

• d5z0sb_ is new in SCOPe 2.07-stable
  
• d5z0sb_ appears in the current release, SCOPe 2.08