SCOPe 2.07: Domain d6guec1: 6gue C:1-296

Lineage for d6guec1 (6gue C:1-296)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (413 PDB entries)
   Uniprot P24941

8. Domain d6guec1: 6gue C:1-296 [360793]
   Other proteins in same PDB: d6guea2, d6gueb1, d6gueb2, d6guec2, d6gued1, d6gued2
   automated match to d4fkla_
   complexed with fb8

Details for d6guec1

PDB Entry: 6gue, 1.99 Å

PDB Description: cdk2/cyclina in complex with azd5438

PDB Compounds: (C:) cyclin-dependent kinase 2

SCOPe Domain Sequences for d6guec1:

Sequence, based on SEQRES records:

>d6guec1 d.144.1.7 (C:1-296) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

Sequence, based on observed residues (ATOM records):

>d6guec1 d.144.1.7 (C:1-296) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevtsmpdykpsfprqdf
skvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

Timeline for d6guec1:

• d6guec1 is new in SCOPe 2.07-stable
  
• d6guec1 appears in the current release, SCOPe 2.08