SCOPe 2.07: Domain d6e35a_: 6e35 A:

Lineage for d6e35a_ (6e35 A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.266: Indolic compounds 2,3-dioxygenase-like [140958] (1 superfamily)
   multihelical; bundle, contains interrupted helices

4. Superfamily a.266.1: Indolic compounds 2,3-dioxygenase-like [140959] (3 families)
   contains heme-dependent enzymes

5. Family a.266.1.2: Indoleamine 2,3-dioxygenase-like [140963] (3 proteins)
   Pfam PF01231; contains extra N-terminal all-alpha subdomain of similar fold to the GST C-terminal domain (47615)

6. Protein automated matches [190585] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187592] (47 PDB entries)

8. Domain d6e35a_: 6e35 A: [355134]
   automated match to d4u72b_
   complexed with cyn, hem, trp, zcw

Details for d6e35a_

PDB Entry: 6e35, 2.41 Å

PDB Description: crystal structure of human indoleamime 2,3-dioxygenase (ido1) in complex with l-trp and cyanide, northeast structural genomics target hr6160

PDB Compounds: (A:) Indoleamine 2,3-dioxygenase 1

SCOPe Domain Sequences for d6e35a_:

Sequence, based on SEQRES records:

>d6e35a_ a.266.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
npqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhltdhksqrlarlvlgci
tmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvlanwkkkdpnkpltye
nmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmqerdtllkalleiasc
lekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyegfwedpkefaggsagq
ssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcslesnpsvrefvlskgda
glreaydacvkalvslrsyhlqivtkyilipasqqpkenktsedpskleakgtggtdlmn
flktvrstteksllk

Sequence, based on observed residues (ATOM records):

>d6e35a_ a.266.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
npqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhltdhksqrlarlvlgci
tmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvlanwkkkdpnkpltye
nmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmqerdtllkalleiasc
lekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyegfwedpkefaggsagq
ssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcslesnpsvrefvlskgda
glreaydacvkalvslrsyhlqivtkyilipasqqpkleakgtggtdlmnflktvrstte
ksllk

Timeline for d6e35a_:

• d6e35a_ is new in SCOPe 2.07-stable
  
• d6e35a_ appears in the current release, SCOPe 2.08