SCOPe 2.07: Domain d6fs8a1: 6fs8 A:1-192

Lineage for d6fs8a1 (6fs8 A:1-192)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.52: Restriction endonuclease-like [52979] (4 superfamilies)
   core: 3 layers, a/b/a; mixed beta-sheet of 5 strands, order 12345; strands 2 &, in some families, 5 are antiparallel to the rest

4. Superfamily c.52.1: Restriction endonuclease-like [52980] (37 families)

5. Family c.52.1.34: PA N-terminal domain [254166] (2 proteins)
   Pfam PF00603; relationship to endonucleases discussed in PubMed 19194458

6. Protein PA N-terminal domain [254375] (7 species)

7. Species Influenza b virus (b/memphis/13/2003) [TaxId:1601067] [354528] (3 PDB entries)

8. Domain d6fs8a1: 6fs8 A:1-192 [354529]
   Other proteins in same PDB: d6fs8a2, d6fs8b2
   automated match to d4nfza_
   complexed with e4z, mn

Details for d6fs8a1

PDB Entry: 6fs8, 1.8 Å

PDB Description: influenza b/memphis/13/03 endonuclease with bound inhibitor, baloxavir acid (bxa)

PDB Compounds: (A:) Polymerase acidic protein

SCOPe Domain Sequences for d6fs8a1:

Sequence, based on SEQRES records:

>d6fs8a1 c.52.1.34 (A:1-192) PA N-terminal domain {Influenza b virus (b/memphis/13/2003) [TaxId: 1601067]}
mdtfitrnfqttiiqkakntmaefsedpelqpamlfnicvhlevcyvisdmnfldeegks
ytalegqgkeqnlrpqyeviegmprtiawmvqrslaqehgietpkyladlfdyktkrfie
vgitkgladdyfwkkkeklgnsmelmifsynqdyslsnessldeegkgrvlsrltelqae
lslknlwqvlig

Sequence, based on observed residues (ATOM records):

>d6fs8a1 c.52.1.34 (A:1-192) PA N-terminal domain {Influenza b virus (b/memphis/13/2003) [TaxId: 1601067]}
mdtfitrnfqttiiqkakntmaefsedpelqpamlfnicvhlevcyvisdmnfllrpqye
viegmprtiawmvqrslaqehgietpkyladlfdyktkrfievgitkgladdyfwkkkek
lgnsmelmifsynqdyslsnessldeegkgrvlsrltelqaelslknlwqvlig

Timeline for d6fs8a1:

• d6fs8a1 is new in SCOPe 2.07-stable
  
• d6fs8a1 appears in the current release, SCOPe 2.08