SCOPe 2.07: Domain d6c4da_: 6c4d A:

Lineage for d6c4da_ (6c4d A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d6c4da_: 6c4d A: [349961]
   automated match to d4itjb_
   complexed with ejp

Details for d6c4da_

PDB Entry: 6c4d, 2.52 Å

PDB Description: structure based design of rip1 kinase inhibitors

PDB Compounds: (A:) Receptor-interacting serine/threonine-protein kinase 1

SCOPe Domain Sequences for d6c4da_:

Sequence, based on SEQRES records:

>d6c4da_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nvikmkssdflesaeldsggfgkvslafhrtqglmimktvykgpnciehnealleeakmm
nrlrhsrvvkllgviieegkyslvmeymekgnlmhvlkaemstplsvkgriileiiegma
ylhgkgvihkdlkpenilvdndfhikiadlglasfkmwsklnneehnelrevdgtakkng
gtlyymapehlndvnakpteksdvysfavvlwaifankepyenaiaeqqlimaiksgnrp
dvdditeycpreiislmklcweanpearptfpgieekfrpfylsqle

Sequence, based on observed residues (ATOM records):

>d6c4da_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nvikmkssdflegfgkvslafhrtqglmimktvykgpnciehnealleeakmmnrlrhsr
vvkllgviieegkyslvmeymekgnlmhvlkaemstplsvkgriileiiegmaylhgkgv
ihkdlkpenilvdndfhikiadlglasfkmwsklnneehngtlyymapehlndvnakpte
ksdvysfavvlwaifankepyenaiaeqqlimaiksgnrpdvdditeycpreiislmklc
weanpearptfpgieekfrpfylsqle

Timeline for d6c4da_:

• d6c4da_ is new in SCOPe 2.07-stable
  
• d6c4da_ appears in the current release, SCOPe 2.08