SCOPe 2.07: Domain d5kvta1: 5kvt A:501-787

Lineage for d5kvta1 (5kvt A:501-787)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d5kvta1: 5kvt A:501-787 [346560]
   Other proteins in same PDB: d5kvta2
   automated match to d5ut3a_
   complexed with gol, ymx

Details for d5kvta1

PDB Entry: 5kvt, 2.45 Å

PDB Description: the structure of trka kinase domain bound to the inhibitor entrectinib

PDB Compounds: (A:) high affinity nerve growth factor receptor

SCOPe Domain Sequences for d5kvta1:

Sequence, based on SEQRES records:

>d5kvta1 d.144.1.0 (A:501-787) automated matches {Human (Homo sapiens) [TaxId: 9606]}
cvhhikrrdivlkwelgegafgkvflaechnllpeqdkmlvavkalkeasesarqdfqre
aelltmlqhqhivrffgvctegrpllmvfeymrhgdlnrflrshgpdakllaggedvapg
plglgqllavasqvaagmvylaglhfvhrdlatrnclvgqglvvkigdfgmsrdiystdy
yrvggrtmlpirwmppesilyrkfttesdvwsfgvvlweiftygkqpwyqlsnteaidci
tqgrelerpracppevyaimrgcwqrepqqrhsikdvharlqalaqa

Sequence, based on observed residues (ATOM records):

>d5kvta1 d.144.1.0 (A:501-787) automated matches {Human (Homo sapiens) [TaxId: 9606]}
cvhhikrrdivlkwelgegafgkvflaechnldkmlvavkalkeasesarqdfqreaell
tmlqhqhivrffgvctegrpllmvfeymrhgdlnrflrshgpdakllaggedvapgplgl
gqllavasqvaagmvylaglhfvhrdlatrnclvgqglvvkigdfgmsrdiystdyyrvg
grtmlpirwmppesilyrkfttesdvwsfgvvlweiftygkqpwyqlsnteaidcitqgr
elerpracppevyaimrgcwqrepqqrhsikdvharlqalaqa

Timeline for d5kvta1:

• d5kvta1 is new in SCOPe 2.07-stable
  
• d5kvta1 appears in the current release, SCOPe 2.08