SCOPe 2.07: Domain d6b3sg1: 6b3s G:1-107

Lineage for d6b3sg1 (6b3s G:1-107)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.0: automated matches [191470] (1 protein)
   not a true family

6. Protein automated matches [190740] (29 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187920] (1626 PDB entries)

8. Domain d6b3sg1: 6b3s G:1-107 [342348]
   Other proteins in same PDB: d6b3sa1, d6b3sa2, d6b3sb1, d6b3sb2, d6b3sb3, d6b3se1, d6b3se2, d6b3se3, d6b3si1, d6b3si2, d6b3si3
   automated match to d3b2ud1
   complexed with bma, man, nag

Details for d6b3sg1

PDB Entry: 6b3s, 2.8 Å

PDB Description: crystal structure of the fab fragment of necitumumab (fab11f8) in complex with domain iii from a cetuximab resistant variant of egfr (segfrd3-s468r)

PDB Compounds: (G:) Necitumumab Fab Light chain

SCOPe Domain Sequences for d6b3sg1:

Sequence; same for both SEQRES and ATOM records:

>d6b3sg1 b.1.1.0 (G:1-107) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eivmtqspatlslspgeratlscrasqsvssylawyqqkpgqaprlliydasnratgipa
rfsgsgsgtdftltisslepedfavyychqygstpltfgggtkaeik

Timeline for d6b3sg1:

• d6b3sg1 first appeared in SCOPe 2.06
  
• d6b3sg1 appears in the current release, SCOPe 2.08