SCOPe 2.07: Domain d5neva1: 5nev A:1-295

Lineage for d5neva1 (5nev A:1-295)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (413 PDB entries)
   Uniprot P24941

8. Domain d5neva1: 5nev A:1-295 [332477]
   Other proteins in same PDB: d5neva2, d5nevb1, d5nevb2, d5nevc2, d5nevd1, d5nevd2
   automated match to d1giia_
   complexed with 72l

Details for d5neva1

PDB Entry: 5nev, 2.97 Å

PDB Description: cdk2/cyclin a in complex with compound 73

PDB Compounds: (A:) cyclin-dependent kinase 2

SCOPe Domain Sequences for d5neva1:

Sequence; same for both SEQRES and ATOM records:

>d5neva1 d.144.1.7 (A:1-295) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvph

Timeline for d5neva1:

• d5neva1 first appeared in SCOPe 2.06
  
• d5neva1 appears in the current release, SCOPe 2.08