SCOPe 2.07: Domain d3u84b1: 3u84 B:2-230

Lineage for d3u84b1 (3u84 B:2-230)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.389: Menin N-terminal domain-like [310556] (1 superfamily)
   Some structural similarity to cysteine proteinases (d.3.1.4) noted in PubMed 22327296

4. Superfamily d.389.1: Menin N-terminal domain-like [310582] (1 family)
   Pfam PF05053

5. Family d.389.1.1: Menin N-terminal domain-like [310623] (2 proteins)

6. Protein Menin N-terminal domain [310724] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [310972] (34 PDB entries)

8. Domain d3u84b1: 3u84 B:2-230 [306640]
   Other proteins in same PDB: d3u84b2
   automated match to d3u85a1

Details for d3u84b1

PDB Entry: 3u84, 2.5 Å

PDB Description: crystal structure of human menin

PDB Compounds: (B:) Menin

SCOPe Domain Sequences for d3u84b1:

Sequence, based on SEQRES records:

>d3u84b1 d.389.1.1 (B:2-230) Menin N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
glkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrviptnvpel
tfqpspapdppggltyfpvadlsiiaalyarftaqirgavdlslypreggvssrelvkkv
sdviwnslsrsyfkdrahiqslfsfitgtkldssgvafavvgacqalglrdvhlalsedh
awvvfgpngeqtaevtwhgkgnedrrgqtvnagvaerswlylkgsymrc

Sequence, based on observed residues (ATOM records):

>d3u84b1 d.389.1.1 (B:2-230) Menin N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
glkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrviptnvpel
tfqpspapdltyfpvadlsiiaalyarftaqirgavdlslypreggvssrelvkkvsdvi
wnslsrsyfkdrahiqslfsfitgtkldssgvafavvgacqalglrdvhlalsedhawvv
fgpngeqtaevtwhrrgqtvnagvaerswlylkgsymrc

Timeline for d3u84b1:

• d3u84b1 first appeared in SCOPe 2.06
  
• d3u84b1 appears in the current release, SCOPe 2.08