SCOPe 2.07: Domain d1hwxf4: 1hwx F:209-501

Lineage for d1hwxf4 (1hwx F:209-501)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (12 proteins)
   extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site

6. Protein Glutamate dehydrogenase [51884] (8 species)

7. Species Cow (Bos taurus) [TaxId:9913] [51889] (8 PDB entries)

8. Domain d1hwxf4: 1hwx F:209-501 [302501]
   Other proteins in same PDB: d1hwxa3, d1hwxb3, d1hwxc3, d1hwxd3, d1hwxe3, d1hwxf3
   automated match to d1hwza1
   complexed with glu, gtp, nai

Details for d1hwxf4

PDB Entry: 1hwx, 2.5 Å

PDB Description: crystal structure of bovine liver glutamate dehydrogenase complexed with gtp, nadh, and l-glutamic acid

PDB Compounds: (F:) glutamate dehydrogenase

SCOPe Domain Sequences for d1hwxf4:

Sequence; same for both SEQRES and ATOM records:

>d1hwxf4 c.2.1.7 (F:209-501) Glutamate dehydrogenase {Cow (Bos taurus) [TaxId: 9913]}
hgrisatgrgvfhgienfienasymsilgmtpgfgdktfavqgfgnvglhsmrylhrfga
kcvavgesdgsiwnpdgidpkeledfklqhgtilgfpkakiyegsilevdcdilipaase
kqltksnaprvkakiiaegangpttpqadkiflernimvipdlylnaggvtvsyfqilkn
lnhvsygrltfkyerdsnyhllmsvqeslerkfgkhggtipivptaefqdrisgasekdi
vhsglaytmersarqimrtamkynlgldlrtaayvnaiekvfrvyneagvtft

Timeline for d1hwxf4:

• d1hwxf4 first appeared in SCOPe 2.06
  
• d1hwxf4 appears in the current release, SCOPe 2.08