SCOPe 2.07: Domain d4l98a_: 4l98 A:

Lineage for d4l98a_ (4l98 A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (167 PDB entries)
   Uniprot P37231 232-505

8. Domain d4l98a_: 4l98 A: [266647]
   automated match to d3ty0a_
   complexed with lrg; mutant

Details for d4l98a_

PDB Entry: 4l98, 2.28 Å

PDB Description: crystal structure of the complex of f360l ppargamma mutant with the ligand lt175

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d4l98a_:

Sequence, based on SEQRES records:

>d4l98a_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
sadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkhi
tplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiy
tmlaslmnkdgvlisegqgfmtreflkslrkplgdfmepkfefavkfnalelddsdlaif
iaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivt
ehvqllqvikktetdmslhpllqeiykdly

Sequence, based on observed residues (ATOM records):

>d4l98a_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
sadlralakhlydsyiksfpltkakarailtgkttdkspfvievairifqgcqfrsveav
qeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvlisegqgfmtrefl
kslrkplgdfmepkfefavkfnalelddsdlaifiaviilsgdrpgllnvkpiediqdnl
lqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikktetdmslhpllqeiy
kdly

Timeline for d4l98a_:

• d4l98a_ first appeared in SCOPe 2.05
  
• d4l98a_ appears in SCOPe 2.06
  
• d4l98a_ appears in the current release, SCOPe 2.08